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ALS and Motor Neuron Disease clinical trials in Massachusetts
6 studies for ALS and Motor Neuron Disease are looking for participants at sites in Massachusetts.
Cities in Massachusetts
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
- Massachusetts General Hospital, Healey & AMG Center for ALS, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT06665165Spastic Paraplegia - Centers of Excellence Research Network
- Boston Children's Hospital, Boston
- Massachusetts General Hospital, Boston
RecruitingObservational study
All ages · All sexes · Updated Mar 18, 2026 · NCT06553976Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
- Boston Children's Hospital, Boston
RecruitingObservational study
1 Month – 30 Years · All sexes · Updated Mar 18, 2026 · NCT05354622Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
- Lahey Hospital and Medical Center, Burlington
RecruitingPhase 3
Ages 18 to 81 · All sexes · Updated Sep 12, 2025 · NCT03127267ALS Research Collaborative
- ALS Therapy Development Institute, Watertown
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 20, 2025 · NCT06885918From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.