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Alzheimer's Disease clinical trials in California
50 studies for Alzheimer's Disease are looking for participants at sites in California.
Cities in California
- Los Angeles14 studies
- Irvine12 studies
- San Diego11 studies
- Long Beach10 studies
- Anaheim9 studies
- San Francisco8 studies
- Orange7 studies
- Mountain View6 studies
- Oakland5 studies
- Concord5 studies
- Santa Ana4 studies
- Riverside4 studies
- San Bernardino3 studies
- Murrieta3 studies
- Burbank3 studies
- Chino3 studies
- Westminster3 studies
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
- Neurobehavioral Systems, Inc., Berkeley
RecruitingHealthy volunteers welcome
Ages 18 to 89 · All sexes · Updated Nov 13, 2026 · NCT04800588A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
- Clinical Site, Anaheim
- Clinical Site, Long Beach
- Clinical Site, Murrieta
- and 3 more
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06887192A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
- Local Institution - 1657, Anaheim
- Local Institution - 1668, Fresno
- Local Institution - 2625, Long Beach
- and 6 more
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 12, 2026 · NCT06937229CMN LIFU for Enhanced Amyloid Reduction (CLEART Study)
- University of California San Francisco, San Francisco
Recruiting
Ages 65 and older · All sexes · Updated Nov 9, 2026 · NCT07866768A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
- Advanced Research Center (ARC) - Anaheim, Anaheim
- Local Institution - 1668, Fresno
- The Neurology Group, Pomona
- and 1 more
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 6, 2026 · NCT07011732A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
- Healthy Brain Clinic- Site Number : 8400011, Long Beach
- Oakland Clinical- Site Number : 8400010, Oakland
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 6, 2026 · NCT07688213A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
- Irvine Center for Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- Inglewood Clinicals, Los Angeles
- and 4 more
RecruitingPhase 3
Ages 55 to 80 · All sexes · Updated Nov 6, 2026 · NCT07717411A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
- CenExel ACT, Anaheim
- Irvine Clinical Research, Irvine
- Collaborative Neuroscience Network - CNS, Los Alamitos
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Nov 5, 2026 · NCT07787169A Study of LY3439539 in Participants With Alzheimer's Disease
- Irvine Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Nov 4, 2026 · NCT07598370A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
- Profound Research LLC, Carlsbad
- Irvine Clinical Research, Irvine
- UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla
- and 1 more
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
- National Institute of Clinical Research, Garden Grove
- Local Institution - 2607, Long Beach
- Accellacare, Long Beach
- and 4 more
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Nov 3, 2026 · NCT07011745A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
- Advanced Research Center, Inc, Anaheim
- Sunwise Clinical Research, Walnut Creek
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Nov 3, 2026 · NCT06540833A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
- Care Access - Huntington Beach, Huntington Beach
- Irvine Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- and 6 more
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Oct 28, 2026 · NCT07602582A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Healthy Brain Clinic, Long Beach
- Anderson Clinical Research, Redlands
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 27, 2026 · NCT06976216A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
- Advanced Research Center, Inc., Anaheim
- Inland Psychiatric Medical Group (IPMG)-Chino, Chino
- USC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC), Los Angeles
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Oct 27, 2026 · NCT06585787Alzheimer's Tau Platform: Master Protocol
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 50 to 80 · All sexes · Updated Oct 26, 2026 · NCT06957418[18F]PI-2620 Phase 3 Histopathological Study
- UC Los Angeles, Los Angeles
- Esperanza Clinical, Murrieta
- Sutter Health, San Francisco
RecruitingPhase 3
Ages 50 and older · All sexes · Updated Oct 23, 2026 · NCT05641688A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
- CenExel ACT, Anaheim
- Irvine Clinical Research, Irvine
- Collaborative Neuroscience Network - CNS, Los Alamitos
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Oct 22, 2026 · NCT07787182A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
- Irvine Clinical Research ( Site 1041), Irvine
- Healthy Brain Clinic ( Site 1005), Long Beach
- Inglewood Clinical ( Site 1062), Los Angeles
- and 3 more
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Oct 20, 2026 · NCT07033494Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
- Sun Valley Research Center, Inc., Imperial
- Irvine Center for Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- and 5 more
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Oct 19, 2026 · NCT07177352A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
- Progeny Psychiatric Clinic - Irvine, Irvine
- ATP Clinical Research, Inc - Orange, Orange
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Oct 19, 2026 · NCT07633470Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
- CSMC, Los Angeles
Recruiting
Ages 55 to 89 · All sexes · Updated Oct 13, 2026 · NCT07224607A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Fullerton Neurology and Headache Center, Fullerton
- Irvine Clinical Research, Irvine
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 8, 2026 · NCT06976203Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
- Esperanza Clinical, Murrieta
- Oakland Clinical Research, Oakland
- ATP Clinical Research, Inc., Orange
- and 2 more
RecruitingPhase 2
Ages 55 to 80 · All sexes · Updated Oct 7, 2026 · NCT06847321Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
- Local Institution - 0017, Anaheim
- Inland Psychiatric Medical Group., Chino
- Kaizen Brain Center, La Jolla
- and 2 more
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Oct 6, 2026 · NCT06808984A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
- CenExel ACT (Formerly Anaheim Clinical Trials; LLC), Anaheim
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 24, 2026 · NCT07780383Predicting Pre-dementia
- Foster Carr MD, San Diego
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 22, 2026 · NCT07516119A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
- Irvine Center for Clinical Research /ID# 277752, Irvine
RecruitingPhase 1/2
Ages 50 to 90 · All sexes · Updated Sep 18, 2026 · NCT07599670Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
- Saddleback Medical Center, Orange
Recruiting
Ages 70 and older · All sexes · Updated Sep 8, 2026 · NCT05929703Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)
- UCLA TMS Clinical and Research Service, Los Angeles
RecruitingPhase 1/2
Ages 55 to 100 · All sexes · Updated Sep 4, 2026 · NCT06597942Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
- Stanford Medical Center, Palo Alto
Recruiting
Ages 50 and older · All sexes · Updated Aug 24, 2026 · NCT07178210Senicapoc in Alzheimer's Disease
- University of California, Davis Alzheimer's Disease Center, Sacramento
- UC Davis Alzheimer's Disease Center East Bay, Walnut Creek
RecruitingPhase 2Healthy volunteers welcome
Ages 55 to 85 · All sexes · Updated Aug 17, 2026 · NCT04804241Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the Lifespan
- The Neurology Center of Southern California, Carlsbad
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Aug 17, 2026 · NCT07763392Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
- University of California, San Diego (UCSD) - Medical Center, La Jolla
- University of California, Los Angeles (UCLA) - David Geffen School of Medicine, Los Angeles
- University of California, San Francisco (UCSF), San Francisco
- and 1 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of California San Diego Medical Center, La Jolla
- University of Southern Califonria, Los Angeles
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
- University of California San Diego Medical Center, La Jolla
- University of Southern Califonria, Los Angeles
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
- Inland Psychiatric Medical Group., Chino
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Jun 30, 2026 · NCT06947941Polyphenols and Cognitive Decline
- University of California, Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Jun 11, 2026 · NCT06507254A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)
- Collaborative Neuroscience Network - CNS, Los Alamitos
RecruitingPhase 1Healthy volunteers welcome
Ages 45 to 85 · All sexes · Updated Jun 4, 2026 · NCT06657768TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
- Shiley Marcos Alzheimer's Disease Center, San Diego
RecruitingPhase 1Healthy volunteers welcome
Ages 60 and older · All sexes · Updated May 26, 2026 · NCT06548191From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.