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Alzheimer's Disease clinical trials in Missouri

28 studies for Alzheimer's Disease are looking for participants at sites in Missouri.

Cities in Missouri

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

  • Tekton Research Saint Louis Psychiatry, St Louis
  • Psympatica, LLC, St Louis
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470

Dominantly Inherited Alzheimer Network (DIAN)

  • Washington University in St. Louis School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

  • Citizens Memorial Hospital District, Bolivar
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

  • Tekton Research, LLC - Saint Louis Psychiatry - PPDS, St Louis
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

  • Washington University School of MedicineClinical Translational Research Unit, St Louis
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

  • Clinical Research Professionals - Headlands, Chesterfield
RecruitingPhase 2
Ages 55 to 80 · All sexes · Updated Sep 21, 2026 · NCT06847321

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

  • Local Institution - 1667, St Louis
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 16, 2026 · NCT07011732

Study to Understand Novel Biomarkers in Researching Dementia

  • Washington University School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 60 and older · All sexes · Updated Sep 11, 2026 · NCT06547099

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

  • Clinical Research Professionals ( Site 1004), Chesterfield
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Aug 26, 2026 · NCT07033494

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • St. Luke's Hospital of Kansas City, Kansas City
  • Washington University in St. Louis, St Louis
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis

  • Washington University in St. Louis, St Louis
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Jul 29, 2026 · NCT07695701

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

  • Washington University in St. Louis, St Louis
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

  • Washington University in St. Louis, St Louis
RecruitingPhase 2/3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157

DORA and LP in Alzheimer's Disease Biomarkers

  • Washington University in St. Louis, School of Medicine, St Louis
RecruitingPhase 2Healthy volunteers welcome
Ages 65 and older · All sexes · Updated Jul 13, 2026 · NCT06274528

Sleep Trial to Prevent Alzheimer's Disease

  • Washington University School of Medicine, St Louis
RecruitingPhase 2Healthy volunteers welcome
Ages 65 and older · All sexes · Updated Jul 13, 2026 · NCT04629547

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

  • Citizens Memorial Hospital District, Bolivar
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

  • Citizens Memorial Hospital Neurology CLinic, Bolivar
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

  • Washington University School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Jun 9, 2026 · NCT06129838

Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl

  • Washington University School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT06439992

F 18 T807 Tau PET Imaging of Alzheimer's Disease

  • Washington University School of Medicine, St Louis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT02414347

Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

  • Washington University School of Medicine, St Louis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04579120

Trial-Ready Cohort-Down Syndrome (TRC-DS)

  • Washington University, St. Louis, St Louis
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Late Onset Alzheimer's Disease

  • Joanne Norton, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated May 18, 2026 · NCT05010603

Alzheimer"s Imaging Biomarkers in Obesity

  • Washington University School of Medicine, St Louis
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 60 · All sexes · Updated May 11, 2026 · NCT05077579

Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain

  • Washington University in St. Louis School of Medicine, St Louis
Recruiting
Ages 45 and older · All sexes · Updated May 5, 2026 · NCT06978166

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

  • Washington University in St. Louis, St Louis
RecruitingPhase 1
Ages 21 to 80 · All sexes · Updated Jan 27, 2026 · NCT06372821

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

  • University of Missouri, Columbia
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Aug 13, 2025 · NCT07120347

Imaging Biomarkers in Preclinical and Symptomatic AD

  • Washington University School of Medicine, St Louis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 7, 2025 · NCT04134923

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.