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Appendicitis clinical trials recruiting in the U.S.
6 studies for Appendicitis are recruiting participants at sites across the United States.
You don't have to be young to have appendicitis. Learn to identify signs, symptoms and more about this painful and serious condition.
Recently updated studies
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
Recruiting
Ages 3 to 18 · All sexes · Updated May 13, 2026 · NCT06395636Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study
RecruitingObservational studyHealthy volunteers welcome
Ages 7 and older · All sexes · Updated May 12, 2026 · NCT07579312APPI-Cost Trial for Perforated Appendicitis
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06705842Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon
Recruiting
Ages 18 and older · All sexes · Updated Aug 29, 2025 · NCT04168866PAINED: Project Addressing INequities in the Emergency Department
Recruiting
Ages 0 and older · All sexes · Updated Jul 17, 2025 · NCT05488080Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
Recruiting
Ages 18 and older · All sexes · Updated Apr 29, 2025 · NCT06948071From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.