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Brain Tumors clinical trials in California
40 studies for Brain Tumors are looking for participants at sites in California.
Cities in California
- Los Angeles17 studies
- San Francisco10 studies
- Baldwin Park7 studies
- Mountain View7 studies
- San Diego7 studies
- Orange3 studies
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
- UCSD Moores Cancer Center, La Jolla
- Cedars-Sinai Medical Center, Los Angeles
- UC Irvine Health, Orange
- and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07326566S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
- City of Hope Comprehensive Cancer Center, Duarte
- USC / Norris Comprehensive Cancer Center, Los Angeles
- Contra Costa Regional Medical Center, Martinez
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03418961A Phase I Clinical Study of YN003 in the Treatment of Glioma
- University of California, Los Angeles (UCLA), Los Angeles
- University of California, San Francisco (UCSF), San Francisco
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Nov 10, 2026 · NCT07929909cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- City of Hope, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
- Local Institution - 0096, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07492680Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
- Children's Hospital Los Angeles, Los Angeles
RecruitingPhase 2
Ages 1 to 26 · All sexes · Updated Oct 28, 2026 · NCT07680439A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
- University of California, San Francisco, San Francisco
- Providence - Saint John's Health Center, Santa Monica
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07428616Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
- University of California, Irvine, Irvine
- University of California Los Angeles, Los Angeles
- University of California at San Francisco, San Francisco
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06810544REMASTer: REcurrent Brain Metastases After SRS Trial
- UCLA, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT05124912A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab
- City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT07619599CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
- City of Hope Medical Center, Duarte
- Children's Hospital Los Angeles, Los Angeles
RecruitingPhase 1
Ages 4 to 25 · All sexes · Updated Oct 15, 2026 · NCT04510051Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
- The Angeles clinic - A cedars SINAI AFFILIATE, Los Angeles
- USC Norris Comprehensive Cancer Center, Los Angeles
- University of California, San Francisco (UCSF), San Francisco
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05786924Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
- Hoag Memorial Hospital Presbyterian, Newport Beach
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Oct 13, 2026 · NCT05317858Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
- Providence Medical Foundation, Fullerton
- California Research Institute, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT05386108GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults
- Lucile Packard Children's Hospital Stanford, Palo Alto
RecruitingPhase 1
Ages 1 to 30 · All sexes · Updated Oct 9, 2026 · NCT07087002Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
- Stanford Cancer Center, Stanford
RecruitingPhase 1/2
6 Months – 25 Years · All sexes · Updated Sep 29, 2026 · NCT04085887Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
- Precision NextGen Oncology, Beverly Hills
- OPN Healthcare, Inc, Glendale
- University of Southern California, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
- Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT04977375PilotStudyAssessSafeActiveSurveillancApproachLocalThe Pa w/BrainMetsUndergoinCNSPenetratSystemicThe
- Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07827001Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
- Lucille Packard Children's Hospital Stanford, Palo Alto
RecruitingPhase 2
59 Months · All sexes · Updated Sep 15, 2026 · NCT05535166A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
- Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank
- Epic Care-Dublin, Dublin
- Bay Area Breast Surgeons Inc, Emeryville
- and 9 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013A Phase 1/1b Study of IAM1363 in HER2 Cancers
- UCSD Moores Cancer Center, La Jolla
- USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions
- Moores Cancer Center, San Diego
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04343157Fluoroethyltyrosine for the Evaluation of Intracranial Neoplasm
- University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 4 and older · All sexes · Updated Aug 27, 2026 · NCT06474533A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases
- City of Hope--Duarte, Duarte
- Univ. of California Los Angeles, Los Angeles
- Scripps Health, San Diego
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06764940Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
- Eden Medical Center, Castro Valley
- UCSD Moores Cancer Center, La Jolla
- MemorialCare Health System, Laguna Hills
- and 2 more
RecruitingObservational study
All ages · All sexes · Updated Jul 22, 2026 · NCT04427384Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
- Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06580002An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis
- City of Hope Medical Center, Duarte
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT05376878Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
- Stanford University School of Medicine, Palo Alto
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT03510208Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients
- Moores Cancer Center, San Diego
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Jun 10, 2026 · NCT05576103Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
- City of Hope Corona, Corona
- City of Hope Comprehensive Cancer Center, Duarte
- City of Hope at Irvine Lennar, Irvine
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT03550391Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma
- University of California San Francisco, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT07418775Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases
- Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06712927Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
- Stanford University, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT05987644Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
- The University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT05452005Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT06650163Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT07339085APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
- Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)
- University of California, San Francisco (UCSF), San Francisco
RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Feb 22, 2024 · NCT06118723The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
- University of California, San Francisco, San Francisco
RecruitingObservational study
Up to age 90 · All sexes · Updated Feb 22, 2024 · NCT06273176From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.