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Brain Tumors clinical trials in Los Angeles, CA

16 studies for Brain Tumors are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

RecruitingPhase 1/2
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT04977375

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • The Angeles clinic - A cedars SINAI AFFILIATE, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

RecruitingPhase 1/2
  • California Research Institute, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

RecruitingPhase 2
  • Univ. of California Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06764940

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Children's Hospital Los Angeles, Los Angeles
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

REMASTer: REcurrent Brain Metastases After SRS Trial

Recruiting
  • UCLA, Los Angeles
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05124912

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • University of California Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

RecruitingPhase 1
  • Children's Hospital Los Angeles, Los Angeles
Ages 4 to 25 · All sexes · Updated Mar 5, 2026 · NCT04510051

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

RecruitingPhase 1
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT06650163

Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis

Recruiting
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT07339085

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • USC / Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

RecruitingPhase 2
  • Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224

About Brain Tumors

A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.

More about Brain Tumors on MedlinePlus

Brain Tumors trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.