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Breast Cancer clinical trials in California
180 studies for Breast Cancer are looking for participants at sites in California.
Cities in California
- Los Angeles73 studies
- Baldwin Park43 studies
- San Diego41 studies
- San Francisco40 studies
- Santa Monica29 studies
- Mountain View27 studies
- Irvine23 studies
- Sacramento19 studies
- Newport Beach13 studies
- Orange11 studies
- Santa Rosa11 studies
- Torrance11 studies
- Vallejo10 studies
- Concord9 studies
- Burbank9 studies
- Fullerton8 studies
- Long Beach8 studies
- Stockton8 studies
- Oakland7 studies
- Santa Clara7 studies
- Roseville7 studies
- Richmond7 studies
- San Jose7 studies
- Huntington Beach7 studies
- Indio6 studies
- Westminster6 studies
- Santa Barbara6 studies
- Anaheim6 studies
- Pleasanton6 studies
- Fresno6 studies
- Redwood City6 studies
- Fremont5 studies
- Modesto5 studies
- Santa Maria5 studies
- Clovis4 studies
- Alhambra4 studies
- Whittier4 studies
- San Bernardino4 studies
- Bakersfield4 studies
- Vacaville4 studies
- Riverside4 studies
- San Leandro4 studies
- Antioch4 studies
- Daly City4 studies
- Glendale4 studies
- Elk Grove4 studies
- Arden-Arcade4 studies
- Pasadena4 studies
- Upland3 studies
- San Marcos3 studies
- Sunnyvale3 studies
- Carlsbad3 studies
- Santa Clarita3 studies
- Ontario3 studies
- Bellflower3 studies
A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes
- Community Cancer Institute (CCI), Clovis
- The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Cente, Torrance
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07748208Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
- Providence Medical Foundation - Santa Rosa, CA, Santa Rosa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT05696626A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
- Disney Family Cancer Center, Burbank
- City of Hope, Corona
- City of Hope Comprehensive Cancer Center, Duarte
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT05894239Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
- UCLA Hematology/Oncology - Parkside ( Site 0021), Santa Monica
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06797635Post-Marketing Study for Early-Stage Low-Risk Breast Cancer Treatment Using ProSense® Cryoablation (ChoICE Trial)
- Glendale Adventist Medical Center d/b/a Adventist Health Glendale, Glendale
Recruiting
Ages 70 and older · All sexes · Updated Nov 12, 2026 · NCT07629206A Study Evaluating Adherence, Tolerability, and Patient Reported Outcomes of Giredestrant in Participants With ER+/HER2- Early Breast Cancer Who Are Intolerant to Adjuvant Aromatase Inhibitor Therapy (novERA Breast Cancer)
- Community Cancer Institute (CCI), Clovis
- Orange Coast Medical Center, Fountain Valley
- Stockton Hematology Oncology Medical Group-2626 N California St, Stockton
RecruitingPhase 3
Ages 18 and older · Women · Updated Nov 12, 2026 · NCT07541079BostonGene and Exigent Genomic INsight Study
- Stockton Hematology Oncology Medical Group, Stockton
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06272864S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
- City of Hope Comprehensive Cancer Center, Duarte
- USC / Norris Comprehensive Cancer Center, Los Angeles
- Contra Costa Regional Medical Center, Martinez
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03418961Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
- Keck Medicine of USC Koreatown, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
- and 1 more
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Nov 12, 2026 · NCT05372640Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
- Research Facility, Irvine
- Research Facility, San Diego
- Research Facility, Santa Monica
RecruitingPhase 1/2
All ages · All sexes · Updated Nov 12, 2026 · NCT06590857A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
- Beverly Hills Cancer Center, Beverly Hills
- Hoag Memorial Hospital Presbyterian, Newport Beach
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06827236A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
- Roy and Patricia Disney Family Cancer Center ( Site 0055), Burbank
- Community Cancer Institute ( Site 0100), Clovis
- Providence Medical Foundation ( Site 0080), Fullerton
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06966700Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
- Ellison Institute, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT04557449Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
- City of Hope Medical Center, Duarte
- City of Hope at Irvine Lennar, Irvine
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06260033Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer
- City of Hope Medical Center, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07664579ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
- City of Hope, Duarte
- UC San Diego Moores Cancer Center, La Jolla
- UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07007559A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
- City of Hope - Duarte, Duarte
- City of Hope - Orange County Lennar Foundation Cancer Center, Irvine
- University of California San Diego (UCSD) - Koman Family Outpatient Pavilion ? La Jolla, La Jolla
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT03424005The Vanguard Study: Testing a New Way to Screen for Cancer
- Kaiser Permanente-Division of Research, Pleasanton
- Naval Medical Center -San Diego, San Diego
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry)
- University of California, San Diego, San Diego
- University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT05964504A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
- City of Hope, Duarte
- UC San Diego Moores Cancer Center, La Jolla
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07029399Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
- The Oncology Institute of Hope and Innovation, Cerritos
- Ellison Medical Institute, Los Angeles
- Valkyrie Clinical Trials, Los Angeles
- and 3 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06324357INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study
- University of California Los Angeles (UCLA), Los Angeles
RecruitingMentions payment for participants
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07671937A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
- City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07318805Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
- Marin Cancer Care, Greenbrae
- Loma Linda University, Loma Linda
- Cancer and Blood Research Center, Los Alamitos
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07214532Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
- City of Hope, Duarte
- City of Hope, Huntington Beach
- City of Hope, Irvine
- and 2 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT05315700Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
- Beverly Hills Cancer Center, Beverly Hills
- City of Hope National Medical Center, Duarte
- Cedars-Sinai Medical Center, Los Angeles
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06982521A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- Community Cancer Institute, Clovis
- City of Hope, Duarte
- Epic Care - Emeryville, Emeryville
- and 17 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07174336A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
- Disney Family Cancer Center, Burbank
- City of Hope - Lennar Foundation Cancer Center, Irvine
- Scripps Health, La Jolla
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06790693cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- City of Hope, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881E-Mindfulness Approaches for Living After Breast Cancer
- Kaiser Permanente-Anaheim, Anaheim
- Kaiser Permanente-Deer Valley Medical Center, Antioch
- AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
- and 56 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
- City of Hope, Duarte
- City of Hope Orange County Lennar Foundation Cancer Center, Irvine
- USC/Norris Comprehensive Cancer Center, Los Angeles
- and 1 more
RecruitingPhase 2
Ages 18 and older · Women · Updated Nov 4, 2026 · NCT07287098Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- PCR Oncology, Arroyo Grande
- AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
- and 22 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
- University of California Los Angeles Medical Center, Los Angeles
- University of California, San Diego; Moores Cancer Center, San Diego
- USOR Sansum Clinic, Santa Barbara
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05579366Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- Kaiser Permanente-Deer Valley Medical Center, Antioch
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- PCR Oncology, Arroyo Grande
- and 39 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06418204A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
- University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06400472A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
- Hoag Memorial Hospital Presbyterian, Newport Beach
- Stanford University Medical Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07213791A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- City of Hope, Duarte
- University of California, Los Angeles (UCLA), Santa Monica
- Stanford University Medical Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07114601Distance-Based Exercise to Preserve Function and Prevent Disability
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- City of Hope - Duarte Cancer Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06760819Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
- Kaiser Permanente-Anaheim, Anaheim
- Kaiser Permanente-Deer Valley Medical Center, Antioch
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- and 107 more
RecruitingPhase 3
Ages 18 to 60 · Women · Updated Nov 4, 2026 · NCT05879926From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.