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Breast Cancer clinical trials in Honolulu, HI

12 studies for Breast Cancer are looking for participants at sites in and around Honolulu (within about 30 miles). Open a study to see who can join and how to contact the study team.

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Honolulu
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Kaiser Permanente Moanalua Medical Center, Honolulu
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Kaiser Permanente Hawaii Moanalua Medical Center, Honolulu
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

A Prospective Study to Develop and Clinically Validate an in Vitro Diagnostic Medical Device That Uses Blood to Classify Patients at High Risk for Breast Cancer

RecruitingObservational study
  • Univercity of Hawaii Cancer Center, Honolulu
Ages 40 and older · Women · Updated Sep 10, 2026 · NCT06672302

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Kaiser Permanente Moanalua Medical Center, Honolulu
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu
  • Queen's Cancer Cenrer - POB I, Honolulu
  • Queen's Medical Center, Honolulu
  • and 13 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Kaiser Permanente Moanalua Medical Center, Honolulu
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

EXoPERT EMERALD Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Hawaii Cancer Center, Honolulu
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • Spark M. Matsunaga VA Medical Center, Honolulu
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu
  • Queen's Cancer Cenrer - POB I, Honolulu
  • Queen's Medical Center, Honolulu
  • and 12 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu
  • Queen's Cancer Center - POB I, Honolulu
  • Queen's Medical Center, Honolulu
  • and 9 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer

RecruitingPhase 1
  • Kapi'olani Medical Center for Women & Children, Honolulu
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT02926690

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

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Other studies in Honolulu

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.