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Breast Cancer clinical trials in Dallas, TX
54 studies for Breast Cancer are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.
Study of AVZO-021 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Avenzo Therapeutics Recruiting Site, Dallas
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
RecruitingPhase 3
- Texas Oncology - DFW ( Site 8003), Dallas
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
RecruitingPhase 3
- Research Site, Dallas
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- University of Texas Southwestern Medical Center, Dallas
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
RecruitingPhase 3
- Texas Oncology-Dallas Presbyterian Hospital ( Site 8000), Dallas
- Parkland Health and Hospital System ( Site 0069), Dallas
- UT Southwestern Medical Center ( Site 0050), Dallas
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
RecruitingPhase 3
- Texas Oncology - DFW ( Site 8009), Dallas
- UT Southwestern ( Site 0092), Dallas
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
RecruitingPhase 3
- Clinical Trial Site, Dallas
- Clinical Trial Site, Dallas
ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions
Recruiting
- University of Texas Southwestern Medical Center, Dallas
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- Texas Oncology - DFW (Sammons CC), Dallas
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- Parkland Health and Hospital System, Dallas
- USO - Texas Oncology, Dallas
- UT Southwestern Medical Center, Dallas
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
- Texas Oncology - DFW (Sammons CC), Dallas
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
RecruitingPhase 3
- UT Southwestern Medical Center at Redbird, Dallas
- University Of Texas Southwestern Medical Center, Dallas
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
RecruitingPhase 1/2
- Baylor Scott & White Research Institute -Texas Oncology, Dallas
- UT Southwestern Medical Center, Dallas
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- UT Southwest Simmons Cancer Center, Dallas
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- Texas Oncology - DFW, Dallas
Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
RecruitingPhase 2
- Texas Oncology - DFW ( Site 8000), Dallas
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- SCRI at Mary Crowley, Dallas
- University of Texas Southwestern Medical Center, Dallas
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- Mary Crowley Cancer Research, Dallas
A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
RecruitingPhase 1
- Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
- UT Southwestern Medical Center, Dallas
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
RecruitingPhase 1/2
- Texas Oncology (Worth) - USOR, Dallas
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
RecruitingPhase 1/2
- Texas Oncology - Dallas SCRI, Dallas
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
RecruitingPhase 3
- Texas Oncology DFW, Dallas
- University of Texas Southwestern Medical Center, Dallas
Susan G. Komen's ShareForCures
RecruitingObservational study
- Susan G. Komen, Dallas
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
- Mary Crowley Cancer Research, Dallas
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
RecruitingPhase 1
- University of Texas Southwestern Medical Center, Dallas
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
RecruitingPhase 2
- Texas Oncology DFW, Dallas
- The University of Texas Southwestern Medical Center, Dallas
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
RecruitingPhase 3
- Texas Oncology - Dallas Presbyterian Hospital, Dallas
- Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas
- The University of Texas Southwestern Medical Center, Dallas
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- Mary Crowley Cancer Research, Dallas
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
RecruitingPhase 2
- Baylor Scott & White Research Institute, Dallas
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- Texas Oncology, Dallas
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
RecruitingPhase 2
- Texas Oncology - DFW, Dallas
Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
RecruitingPhase 2
- UT Southwestern Medical Center-Dallas, Dallas
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
- University of Texas Southwestern, Dallas
A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors
RecruitingPhase 1/2
- Texas Oncology, P.A., Dallas
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
RecruitingPhase 1/2
- Texas Oncology Baylor University Medical Center, Dallas
Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
RecruitingPhase 2
- Parkland Hospital, Dallas
- University of Texas Southwestern Medical Center, Dallas
CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer
RecruitingPhase 1
- UT Southwestern Medical Center, Dallas
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
RecruitingPhase 2
- UT Southwestern Medical Center, Dallas
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
RecruitingPhase 1/2
- Next Oncology, Dallas
- UTSW Medical Center, Dallas
Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
RecruitingPhase 2
- Texas Oncology- DFW, Dallas
Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy
Recruiting
- UT Southwestern, Dallas
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
RecruitingPhase 1/2
- Research Site, Dallas
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
RecruitingPhase 1
- Mary Crowley Cancer Research, Dallas
- Baylor University Medical Center, Dallas
Tirzepatide Weight Loss for MRD+ Early Breast Cancer
RecruitingPhase 2
- Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas
Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC
RecruitingEarly phase 1
- Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas
Converting HR+ Breast Cancer Into an Individualized Vaccine
RecruitingPhase 2
- UT Southwestern Medical Center, Dallas
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
RecruitingPhase 4
- UT Southwestern Medical Center, Dallas
Gene Signatures to Guide HR+MBC Therapy in a Diverse Cohort
RecruitingPhase 2
- UT Southwestern Medical Center, Dallas
Neratinib in Combination With Ruxolitinib in Patients With mTNBC
RecruitingEarly phase 1
- Baylor University Medical Center, Baylor Charles A Sammons Cancer Center, Dallas
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Dallas
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
RecruitingPhase 3
- UT Southwestern/Simmons Cancer Center-Dallas, Dallas
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
RecruitingPhase 1/2
- Mary Crowley Cancer Research, Dallas
- University of Texas Southwestern Medical Center, Dallas
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
RecruitingPhase 1
- University of Texas Southwestern Medical Center, Dallas
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
RecruitingObservational study
- Texas Oncology - Presbyterian, Dallas
- Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY134 studies
- Houston, TX126 studies
- Boston, MA110 studies
- Nashville, TN79 studies
- Los Angeles, CA71 studies
- Edison, NJ69 studies
- St. Louis, MO64 studies
- Durham, NC63 studies
- Queens, NY63 studies
- Chicago, IL58 studies
- Philadelphia, PA56 studies
- Baltimore, MD47 studies
Other studies in Dallas
- Non-Small Cell Lung Cancer52 studies
- Heart Failure42 studies
- Metastatic Cancer42 studies
- Cancer (all types)38 studies
- Prostate Cancer36 studies
- Colorectal Cancer33 studies
- Obesity31 studies
- Ovarian Cancer28 studies
- Bladder Cancer27 studies
- Lung Cancer27 studies
- Endometrial Cancer25 studies
- Pancreatic Cancer23 studies
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.