Home › Cancer (all types) › Illinois
Cancer (all types) clinical trials in Illinois
68 studies for Cancer (all types) are looking for participants at sites in Illinois.
Cities in Illinois
- Chicago51 studies
- Cicero12 studies
- Evanston9 studies
- Peoria7 studies
- Waukegan6 studies
- Champaign5 studies
- Naperville5 studies
- Springfield5 studies
- Aurora4 studies
- Decatur4 studies
- Arlington Heights3 studies
- Charleston3 studies
- Bloomington3 studies
- Danville3 studies
- Carbondale3 studies
- Joliet3 studies
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- University of Illinois Chicago, Chicago
- Illinois Cancer Specialists, Niles
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Nov 13, 2026 · NCT05920356A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
- Hope And Healing Cancer Services /ID# 268536, Hinsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT05650632RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Rush University Medical Center, Chicago
- University of Chicago Medical Center, Chicago
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- OSF Saint Anthony's Health Center, Alton
- Advocate Outpatient Center - Aurora, Aurora
- Advocate Good Shepherd Hospital, Barrington
- and 56 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT06580314Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- Rush University Medical Center, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07195591Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
- University of Illinois Cancer Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT04198766A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- Northwestern Memorial Hospital, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06901531A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
- Hope and Healing Cancer Services, Hinsdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07169851A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- City of Hope Chicago, Zion
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06150157A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- University of Illinois at Chicago, Chicago
- University of Chicago Hospital, Chicago
- Springfield Clinic Main Campus, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06119581Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- Northwestern Memorial Hospital, Chicago
- University Of Chicago Medical Center, Chicago
RecruitingPhase 2/3
All ages · All sexes · Updated Nov 2, 2026 · NCT03435796Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
- Lurie Children's Hospital, Chicago
RecruitingPhase 2
Ages 1 to 26 · All sexes · Updated Oct 28, 2026 · NCT07680439Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
- Hope and Healing Clinical Research LLC, Hinsdale
- Hope and Healing Clinical Research LLC, New Lenox
- Illinois Cancer Specialists, Niles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07566156Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
- Chicago Cancer Center, Zion
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 27, 2026 · NCT05997615Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
- Edward Hines Jr. VA Hospital, Hines, IL, Hines
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT02984761DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies
- Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital), Chicago
RecruitingObservational study
Ages 18 to 75 · All sexes · Updated Oct 21, 2026 · NCT05671887A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
- University of Chicago Medical Center /ID# 278863, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT07409246A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer
- Research Site, Evanston
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 19, 2026 · NCT07647328A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- Cancer Care Specialists of Illinois, Decatur
- Decatur Memorial Hospital, Decatur
- Hope and Healing Clinical Research LLC, Hinsdale
- and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06989437A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)
- Northwestern University ( Site 0101), Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07030712Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
- Carle Cancer Center, Urbana
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT05386108A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
- University of Chicago Medical Center /ID# 274742, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07023289CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
- Northwestern Memorial Hospital, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT03328078uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
- Northwestern University, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921Registry Study for Radiation Therapy Outcomes
- OSF HealthCare Cancer Institute, Peoria
- Northwestern Medicine Chicago Proton Center, Warrenville
RecruitingObservational study
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
- Investigative Site, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06881992A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- University of Chicago Medical Center /ID# 280149, Chicago
- OSF St. Francis Medical Center /ID# 279930, Peoria
- Springfield Clinic - First /ID# 281309, Springfield
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Cancer Treatment Centers of America-Chicago, Chicago
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Evaluating the Communication Between Patients and Providers in Cancer Clinics
- Northwestern Memorial Hospital, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06985953The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
- Rush-Copley Medical Center, Aurora
- Advocate Good Shepherd Hospital, Barrington
- Carle BroMenn Outpatient Center, Bloomington
- and 17 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756607Falcon Real World Evidence Registry
- Endeavor Health, Evanston
RecruitingObservational studyHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Sep 11, 2026 · NCT06589310A Phase 1/1b Study of IAM1363 in HER2 Cancers
- University of Chicago, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
- Northwestern University Feinberg School of Medicine, Chicago
- Cancer Care Specialists of Illinois, Decatur
- Illinois Cancer Care, Peoria
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)
- Ann &Robert H Lurie Children's Hospital, Chicago
RecruitingObservational study
Up to age 30 · Women · Updated Sep 3, 2026 · NCT05309746Ovarian Tissue Cryopreservation in Pre-Pubertal (OTC-Pre Pubertal)
- Ann & Robert H Lurie Childrens Hospital, Chicago
RecruitingObservational study
Up to age 11 · Women · Updated Sep 3, 2026 · NCT05299710Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
- Insight Research Institute, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06252649Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
- Northwestern University, Chicago
- Southern Illinois University-Simmons, Springfield
- Carle Foundation Cancer Institute-Urbana, Urbana
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612Project: Every Child for Younger Patients With Cancer
- Rush-Copley Medical Center, Aurora
- Lurie Children's Hospital-Chicago, Chicago
- Northwestern University, Chicago
- and 16 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Abatacept in Immune Checkpoint Inhibitor Myocarditis
- University of Chicago, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
- University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.