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Cancer (all types) clinical trials in Illinois
69 studies for Cancer (all types) are looking for participants at sites in Illinois.
Cities in Illinois
- Chicago53 studies
- Cicero12 studies
- Evanston10 studies
- Springfield7 studies
- Peoria7 studies
- Champaign7 studies
- Naperville6 studies
- Decatur5 studies
- Waukegan5 studies
- Aurora5 studies
- Danville4 studies
- Arlington Heights4 studies
- Charleston4 studies
- Bloomington4 studies
- Joliet3 studies
- Rockford3 studies
- Carbondale3 studies
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
- Northwest Community Hospital, Arlington Heights
- Rush-Copley Medical Center, Aurora
- Centralia Oncology Clinic, Centralia
- and 28 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05256225Registry Study for Radiation Therapy Outcomes
- OSF HealthCare Cancer Institute, Peoria
- Northwestern Medicine Chicago Proton Center, Warrenville
RecruitingObservational study
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
- University of Chicago Medical Center /ID# 278863, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07409246uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
- Northwestern University, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism
- Investigative Site, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06881992A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- Cancer Care Specialists of Illinois, Decatur
- Decatur Memorial Hospital, Decatur
- Hope and Healing Clinical Research LLC, Hinsdale
- and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- University of Illinois Chicago, Chicago
- Illinois Cancer Specialists, Niles
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- Northwestern Memorial Hospital, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- University of Chicago Medical Center /ID# 280149, Chicago
- OSF St. Francis Medical Center /ID# 279930, Peoria
- Springfield Clinic - First /ID# 281309, Springfield
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Cancer Treatment Centers of America-Chicago, Chicago
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Prospective Study to Assess a Diagnostic Aid for Cancer
- Christie Clinic, Champaign
- Hope and Healing Cancer Services, Hinsdale
- Springfield Clinic, Springfield
RecruitingObservational study
Ages 45 and older · All sexes · Updated Sep 21, 2026 · NCT07046260Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- Northwestern Memorial Hospital, Chicago
- University Of Chicago Medical Center, Chicago
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796Evaluating the Communication Between Patients and Providers in Cancer Clinics
- Northwestern Memorial Hospital, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06985953RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Rush University Medical Center, Chicago
- University of Chicago Medical Center, Chicago
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
- Rush-Copley Medical Center, Aurora
- Advocate Good Shepherd Hospital, Barrington
- Carle BroMenn Outpatient Center, Bloomington
- and 17 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756607Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
- Illinois Cancer Specialists, Niles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07566156Falcon Real World Evidence Registry
- Endeavor Health, Evanston
RecruitingObservational studyHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Sep 11, 2026 · NCT06589310A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001)
- Northwestern University ( Site 0101), Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07030712Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
- Carle Cancer Center, Urbana
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108A Phase 1/1b Study of IAM1363 in HER2 Cancers
- University of Chicago, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- University of Illinois at Chicago, Chicago
- University of Chicago Hospital, Chicago
- Springfield Clinic Main Campus, Springfield
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer
- Research Site, Evanston
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 8, 2026 · NCT07647328A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
- Hope and Healing Cancer Services, Hinsdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07169851A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
- Northwestern University Feinberg School of Medicine, Chicago
- Cancer Care Specialists of Illinois, Decatur
- Illinois Cancer Care, Peoria
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
- Insight Research Institute, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06252649Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)
- Ann &Robert H Lurie Children's Hospital, Chicago
RecruitingObservational study
Up to age 30 · Women · Updated Sep 3, 2026 · NCT05309746Ovarian Tissue Cryopreservation in Pre-Pubertal (OTC-Pre Pubertal)
- Ann & Robert H Lurie Childrens Hospital, Chicago
RecruitingObservational study
Up to age 11 · Women · Updated Sep 3, 2026 · NCT05299710Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
- Northwestern University, Chicago
- Southern Illinois University-Simmons, Springfield
- Carle Foundation Cancer Institute-Urbana, Urbana
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612Project: Every Child for Younger Patients With Cancer
- Rush-Copley Medical Center, Aurora
- Lurie Children's Hospital-Chicago, Chicago
- Northwestern University, Chicago
- and 16 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Abatacept in Immune Checkpoint Inhibitor Myocarditis
- University of Chicago, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
- University of Chicago Medical Center, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies
- Site 05, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07276373Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer
- Tempus AI, Chicago
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Aug 10, 2026 · NCT07756034International Rare Brain Tumor Registry
- Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingObservational study
Up to age 45 · All sexes · Updated Aug 7, 2026 · NCT05697874A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
- Ann & Robert H Lurie Children's Hospital of Chicago, Chicago
RecruitingPhase 2
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- OSF Saint Anthony's Health Center, Alton
- Rush-Copley Medical Center, Aurora
- Advocate Outpatient Center - Aurora, Aurora
- and 58 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
- Lurie Children's Hospital, Chicago
RecruitingPhase 2
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
- The University of Chicago Medicine, Chicago
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
- Hope And Healing Cancer Services /ID# 268536, Hinsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05650632Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions
- Northwestern University, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT07556380From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.