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Cancer (all types) clinical trials in Springfield, IL

7 studies for Cancer (all types) are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05256225

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

RecruitingPhase 3
  • Springfield Clinic - First /ID# 281309, Springfield
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

Prospective Study to Assess a Diagnostic Aid for Cancer

RecruitingObservational study
  • Springfield Clinic, Springfield
Ages 45 and older · All sexes · Updated Sep 21, 2026 · NCT07046260

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Springfield Clinic Main Campus, Springfield
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Southern Illinois University-Simmons, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Saint John's Hospital, Springfield
  • Southern Illinois University School of Medicine, Springfield
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

About Cancer (all types)

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More about Cancer (all types) on MedlinePlus

Cancer (all types) trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.