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Cancer (all types) clinical trials in Pennsylvania
104 studies for Cancer (all types) are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
- Philadelphia60 studies
- Pittsburgh42 studies
- York8 studies
- Allentown7 studies
- Harrisburg5 studies
- Reading4 studies
- Hazleton4 studies
A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
- University of Pennsylvania - Abramson Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07192471A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer
- AHN Allegheny General Hospital, Pittsburgh
- Allegheny General Hospital, Pittsburgh
Recruiting
Ages 20 to 89 · Women · Updated Sep 30, 2026 · NCT07698314Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
- Allegheny General Hospital, Pittsburgh
RecruitingObservational study
Ages 20 to 89 · Women · Updated Sep 30, 2026 · NCT07023887Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Saint Luke's Cancer Center - Allentown, Allentown
- Saint Luke's University Hospital-Bethlehem Campus, Bethlehem
- and 13 more
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05256225EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer
- AHN Allegheny General Hospital, Pittsburgh
- AHN Allegheny General Hospital, Pittsburgh
Recruiting
Ages 20 to 89 · Women · Updated Sep 28, 2026 · NCT07704476A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- University of Pennsylvania, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- Allegheny Health Network, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
- Children's Hospital of Philadelphia (CHOP) ( Site 4021), Philadelphia
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 25, 2026 · NCT07630974A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
- GSK Investigational Site, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07277270A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Alliance Cancer Specialists - Media, Media
- Guthrie Medical Group, Sayre
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors
- UPMC Cancer Centers, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06311578First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors
- GSK Investigational Site, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07438782A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- Allegheny General Hospital (AGH)-Allegheny Singer Research Institute, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531Pan Tumor Rollover Study
- Lancaster General Health, Lancaster
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03899155A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- St. Lukes University Hospital /ID# 280204, Bethlehem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
- Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine ( Site 0100), Philadelphia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07405164Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- Allegheny Health Network, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Lehigh Valley Hospital - Cedar Crest, Allentown
- Lehigh Valley Hospital- Muhlenberg, Bethlehem
- Pocono Medical Center, East Stroudsburg
- and 2 more
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Prospective Study to Assess a Diagnostic Aid for Cancer
- Susquehanna Research Group, Harrisburg
- Respiratory Specialists, Wyomissing
- Cancer Care Associates of York, York
RecruitingObservational study
Ages 45 and older · All sexes · Updated Sep 21, 2026 · NCT07046260Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- University of Pennsylvania Perelman Center for Advanced Medicine, Philadelphia
- Thomas Jefferson University - Clinical Research Institute, Philadelphia
- Fox Chase Cancer Center, Philadelphia
- and 1 more
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
- Children's Hospital of Philadelphia (CHOP) ( Site 3021), Philadelphia
RecruitingPhase 1/2
1 Month – 17 Years · All sexes · Updated Sep 17, 2026 · NCT06941272Collection of Tissue Samples for Cancer Research
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingObservational study
2 Months · All sexes · Updated Sep 16, 2026 · NCT00900198RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- University of Pennsylvania, Philadelphia
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
- Geisinger Medical Center, Danville
- Geisinger Cancer Center Dickson City, Dickson City
- Geisinger Medical Center-Cancer Center Hazleton, Hazleton
- and 4 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756607A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies
- Fox Chase Cancer Center, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06634589A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
- Research Site, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- USO - Alliance Cancer Specialists, PC, Horsham
- Thomas Jefferson University, Sidney Kimmel Cancer Center - Clinical Trials Office, Philadelphia
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
- University of Pennsylvania, Philadelphia
- Cancer Care Associates of York, York
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534Lurbinectedin in FET-Fused Tumors
- Children's Hospital of Philadelphia, Philadelphia
RecruitingPhase 1/2
Ages 10 and older · All sexes · Updated Sep 2, 2026 · NCT05918640IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer
- Thomas Jefferson University, Philadelphia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06206941Project: Every Child for Younger Patients With Cancer
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Geisinger Medical Center, Danville
- Penn State Children's Hospital, Hershey
- and 4 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Abatacept in Immune Checkpoint Inhibitor Myocarditis
- Lehigh Valley Health Network, Bethlehem
- University of Pennsylvania, Philadelphia
- Allegheny-Singer Research Institution, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients
- Fox Chase Cancer Center, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07776704Biennial CEM in Women With a Personal History of Breast Cancer
- UPMC Magee-Womens Imaging - Bethel Park, Bethel Park
- UPMC Magee at the Lemieux Sports Complex, Cranberry Township
- Magee Womancare Monroeville, Monroeville
- and 3 more
RecruitingHealthy volunteers welcome
Ages 30 to 79 · Women · Updated Aug 19, 2026 · NCT06105749A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
- Abramson Cancer Center of the University of Pennsylvania, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer
- AHN Allegheny General Hospital, Pittsburgh
Recruiting
Ages 20 to 89 · Women · Updated Aug 17, 2026 · NCT07739563FOG-001 in Locally Advanced or Metastatic Solid Tumors
- University of Pennsylvania, Perelman School of Medicine, Philadelphia
- University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264Hybrid Type I Effectiveness-implementation Cluster Randomized Controlled Trial of CARES
- University of Pittsburgh Medical Center (UPMC) Cancer Center, Pittsburgh
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07183527A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
- UPMC Children's Hospital of Pittsburgh, Pittsburgh
RecruitingPhase 2
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Saint Luke's Cancer Center - Allentown, Allentown
- Saint Luke's University Hospital-Bethlehem Campus, Bethlehem
- and 21 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.