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Cancer (all types) clinical trials in South Carolina
30 studies for Cancer (all types) are looking for participants at sites in South Carolina.
Cities in South Carolina
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- Medical University of South Carolina, Charleston
RecruitingPhase 3
Ages 18 and older · Women · Updated Sep 29, 2026 · NCT05256225A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- Prisma Health, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Medical University of South Carolina, Florence
- Medical University of South Carolina Health Lancaster Medical Center, Lancaster
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- SC Cancer Specialists at St. Joseph's/Candler Bluffton, Bluffton
- St. Joseph's/Candler Smith, Bluffton
- Summit Cancer Care at St. Josph's/Candler Bluffton, Bluffton
- and 1 more
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- Hematology and Oncology Associates of SC, LLC, Greenville
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)
- Medical University of South Carolina Hollings Cancer Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07227610Evaluating the Communication Between Patients and Providers in Cancer Clinics
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06985953(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
- MUSC Health University Medical Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials
- Saint Joseph's/Candler - Bluffton Campus, Bluffton
- South Carolina Cancer Specialists PC, Hilton Head Island
- The Radiation Oncology Center-Hilton Head/Bluffton, Hilton Head Island
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756607A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Medical University of South Carolina, Charleston
- Prisma Health Cancer Institute, Greenville
- Lexington Medical Center, West Columbia
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581Project: Every Child for Younger Patients With Cancer
- Medical University of South Carolina, Charleston
- Prisma Health Richland Hospital, Columbia
- BI-LO Charities Children's Cancer Center, Greenville
- and 2 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer
- START - Carolinas, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07480356Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- Gibbs Cancer Center-Gaffney, Gaffney
- Gibbs Cancer Center-Pelham, Greer
- Spartanburg Medical Center, Spartanburg
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
- Prisma Health Cancer Institute, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144Optimizing Care for Cancer Survivors With Depression: Project 3
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06930729A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
- Carolina Urologic Research Center, the START Center for Cancer Research, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors
- Medical University of South Carolina Hollings Cancer Center, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07149207Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
- Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
- Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC, Columbia
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06582784A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)
- GSK Investigational Site, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06551142An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors
- Prisma Health-Upstate, Greenville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06487624Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors
- Medical University of South Carolina (MUSC), Charleston
- PRISMA Health, Institute for Translational Oncology, Greenville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06014658Prevent Cancer- Greenville
- Prisma Health-Upstate, Greenville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT04947098GEMINI-NSCLC: NSCLC Biomarker Study
- The Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114Beat Childhood Cancer Specimen Banking and Data Registry
- Medical University of South Carolina, Charleston
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178Reducing Metabolic Dysregulation in Dyads
- University of South Carolina, Columbia
RecruitingHealthy volunteers welcome
Ages 9 to 55 · All sexes · Updated Jan 29, 2026 · NCT06117241Caris Biorepository Research Protocol
- Clinical Biotechnology Research Institute at RSFH, Charleston
- Spartanburg Regional Health Services, Spartanburg
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT01499394SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Greenville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.
- Carolina Blood and Cancer Care Associates, Rock Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2025 · NCT06635954Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.