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Cardiovascular Disease clinical trials in California

52 studies for Cardiovascular Disease are looking for participants at sites in California.

Cities in California

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

  • Pacific Oaks Medical Group, Beverly Hills
  • Cardiovascular Institute of San Diego, Chula Vista
  • John Muir Medical Center - Concord Campus, Concord
  • and 10 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Thrive Clinical Research Group, Glendora
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

  • UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla
  • Valley Clinical Trials, Inc., Northridge
  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294

Product Surveillance Registry

  • Aliso Viejo
  • Chula Vista
  • Colton
  • and 9 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Beverly Hills
  • Clinical Trial Site, Chula Vista
  • Clinical Trial Site, Covina
  • and 20 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Zenith® Fenestrated+ Clinical Study

  • UC San Diego, La Jolla
  • University of Southern California, Los Angeles
  • Stanford Hospitals and Clinics, Stanford
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • National Heart Institute, Beverly Hills
  • Hope Clinical Research, Canoga Park
  • John Muir Physician Network Clinical Research Center, Concord
  • and 11 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Scripps Memorial Hospital, La Jolla
  • PIH Health Good Samaritan Hospital, Los Angeles
  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • and 6 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Single-tracer Multiparametric PET Imaging

  • UC Davis EXPLORER Molecular Imaging Center, Sacramento
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06014515

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

  • Cardiovascular Res Found, Beverly Hills
  • National Heart Institute, Beverly Hills
  • Diabetes Lipid Management Center, Huntington Beach
  • and 7 more
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

  • Clinical Research Site, Santa Barbara
  • Clinical Research Site, Torrance
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Fresno VA Medical Center, Fresno
  • Long Beach VA Medical Center, Long Beach
  • Cedars-Sinai Medical Center, Los Angeles
  • and 3 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

  • City of Hope Comprehensive Cancer Center, Duarte
  • Valley Children's Hospital, Madera
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Beverly Hills
  • Research Site, Canoga Park
  • Research Site, Castroville
  • and 26 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • National Heart Institute, Beverly Hills
  • 310 Clinical Research, Inglewood
  • University of California San Diego, La Jolla
  • and 11 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

WISE CVD - Continuation (WISE HFpEF)

  • Cedars-Sinai Women's Heart Center, Los Angeles
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT02582021

REFOCUS-HTN US-WEST: A Data Infrastructure to Characterize Individuals With Hypertension

  • Kaiser Permanente Northern California, Oakland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07780500

Secondhand Tobacco Smoke and Cardiovascular Disease

  • San Francisco Veterans' Affairs Medical Center, San Francisco
RecruitingPhase 4
Ages 40 and older · All sexes · Updated Aug 19, 2026 · NCT04715568

Global Paradise System US Post Approval Study

  • Tibor Rubin VA Medical Center, Long Beach
  • Cedars-Sinai Medical Center, Los Angeles
  • Sutter Institute for Medical Research, Sacramento
  • and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

  • University of California, Davis, Davis
RecruitingHealthy volunteers welcome
Ages 45 to 70 · Women · Updated Aug 7, 2026 · NCT06476795

ELEVATE-HFpEF Clinical Study

  • Sutter Health Hospital, San Francisco
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841

Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease

  • University of California Davis Health System, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT07717723

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

  • UC San Francisco Medical Center, San Francisco
RecruitingPhase 3
Ages 2 to 11 · All sexes · Updated Jul 24, 2026 · NCT06597006

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

  • UCSF Medical Center at Parnassus, San Francisco
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07087184

kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot

  • UCSF Mission Bay- Sandler Neurosciences Center, San Francisco
Recruiting
Ages 18 to 80 · All sexes · Updated Jul 22, 2026 · NCT07631078

Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans

  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Recruiting
Ages 21 and older · All sexes · Updated Jul 22, 2026 · NCT05423158

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

  • University of California, San Diego, San Diego
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Jun 30, 2026 · NCT07137338

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • USC, Los Angeles
  • UCSF Medical Center, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

SPYRAL GEMINI Pilot Study

  • Stanford Hospital and Clinics, Stanford
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Sutter Medical Center, Sacramento
  • University of California at San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

  • Keck School of Medicine, University of Southern California, Los Angeles
Recruiting
Ages 65 to 84 · All sexes · Updated Jun 8, 2026 · NCT05867381

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

  • UC San Francisco Medical Center, San Francisco
  • UC San Francisco Medical Center, San Francisco
RecruitingPhase 3
Ages 6 to 11 · All sexes · Updated May 15, 2026 · NCT06597019

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

  • VA Greater Los Angeles Healthcare System, North Hills
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Apr 15, 2026 · NCT05516277

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Keck School of Medicine of USC, Los Angeles
  • UCLA Medical Center, Los Angeles
  • Stanford University, Redwood City
  • and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

  • Stanford University Medical Center, Stanford
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

CANF-Comb-II PET-MR in Atherosclerosis Multisite

  • Cedars Sinai Medical Center, Los Angeles
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT05838547

Enhancing Capacity in Churches to Implement PA Programs

  • San Diego State University Research Foundation, San Diego
RecruitingHealthy volunteers welcome
Ages 18 to 65 · Women · Updated Mar 5, 2026 · NCT05473871

Chardonnay Marc and Vascular Response

  • Academic Surge, University of California, Davis, Davis
RecruitingHealthy volunteers welcome
Ages 30 to 50 · Men · Updated Feb 18, 2026 · NCT05545865

Randomized Trial of SGLT2i in Heart Transplant Recipients

  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT06625073

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.