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Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
Who can join
Ages 50 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Community-dwelling Veterans aged 50 years and older * Received care from a Veterans Health Administration (VHA) facility in the prior year * Diagnosis of PTSD * Diagnosis of insomnia disorder * Lives within a 50-mile radius of the research offices at the VA Sepulveda Ambulatory Care Center Exclusion Criteria: * Active substance use or in recovery with less than 90 days of sobriety * Too ill to engage in the study procedures (e.g., unable to attend the in-person meetings) * Unable to self-consent to participate * Unstable housing (as this will impact the research team's ability to retrieve costly and difficult to replace monitoring equipment) * Severe cardiovascular or respiratory disease (e.g., ventilatory failure, CHF) * Unstable medical or psychiatric disorders (which are a contraindication for behavioral treatment of insomnia) * Comorbid sleep disorders (i.e., central sleep apnea syndrome, diagnosed narcolepsy or circadian rhythm sleep-wake phase disorders) based on medical record review and baseline assessment data, or untreated, severe sleep disordered breathing (SDB) as assessed via WatchPAT or previous clinical evaluation (apnea-hypopnea index \[AHI\] ≥ 30; or AHI ≥ 15 plus Epworth Sleepiness Scale \[ESS\] score ≥ 10) that better explain sleep difficulties
About the study
This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of another condition, in the context of PTSD in understudied older adults. This study provides a non-medication treatment for PTSD called Cognitive Processing Therapy (CPT) followed by a non-medication sleep education and treatment program (Cognitive Behavioral Therapy for Insomnia, CBT-I) for sleep problems that remain after completing PTSD treatment in older adults with PTSD. The aims of this project are to evaluate 1) the added benefits of treating residual insomnia on sleep and PTSD symptoms; 2) the added benefits of treating residual insomnia following CPT on cardiometabolic risk biomarkers and quality of life; and 3) the durability of the sleep, PTSD, cardiometabolic and quality of life benefits of treating residual insomnia following CPT at 6-month follow-up in older adults with PTSD.
What is being tested
- Behavioral Sleep Education Intervention (behavioral)
Sponsor: University of California, Los Angeles · Participants: 167 · Started: Apr 1, 2023
Contact the study team
- Monica Kelly, PhD · Phone: 818-891-7711
Official record on ClinicalTrials.gov — NCT05516277
Locations in the U.S.
| California | VA Greater Los Angeles Healthcare System, North Hills |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.