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Cardiovascular Disease clinical trials in Illinois

30 studies for Cardiovascular Disease are looking for participants at sites in Illinois.

Cities in Illinois

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Chicago
  • Clinical Trial Site, Chicago
  • Clinical Trial Site, Hazel Crest
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • Cedar Crosse Research Center, Chicago
  • Accellacare of Duly - Lombard, Lombard
  • Accellacare of Duly, Oak Lawn
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473

A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure

  • Chicago Cardiology Institute, Schaumburg
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Nov 12, 2026 · NCT07584967

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • University of Chicago, Chicago
  • Advocate Health & Hospitals Corporation, Oakbrook Terrace
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Accellacare - DuPage, Lombard
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802

ELEVATE-HFpEF Clinical Study

  • The University of Chicago Medical Center, Chicago
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Northwestern Memorial Hospital, Chicago
  • Rush University Medical Center, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT03242642

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

  • University of Illinois Chicago, Chicago
  • Advocate Aurora Lutheran General Hospital, Park Ridge
  • OSF Multi-Specialty Group, Peoria
  • and 1 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06909565

The TRICURE EFS Study

  • Northwestern, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06506942

Product Surveillance Registry

  • Chicago
RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT01524276

Global Paradise System US Post Approval Study

  • Southern Illinois University, Memorial Medical Center, Springfield
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT06297291

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

  • Jesse Brown VA Medical Center, Chicago, IL, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05931276

Zenith® Fenestrated+ Clinical Study

  • Northwestern Memorial Hospital, Chicago
  • Endeavor Health Cardiovascular Institute at Glenbrook Hospital, Glenview
  • Loyola University Medical Center, Maywood
  • and 1 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04875429

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

  • Clinical Research Site, Chicago
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Northwestern University, Chicago
  • University of Illinois at Chicago, Chicago
  • Chicago VA Medical Center/Jesse Brown VA, Chicago
  • and 4 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

  • Southern Illinois University School of Medicine, Springfield
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Arlington Heights
  • Research Site, Chicago
  • Research Site, Chicago
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • Endeavor Health-Northwest Community Healthcare, Arlington Heights
  • Christie Clinic, Champaign
  • Advocate Lutheran General Hospital, Park Ridge
  • and 1 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial

  • Northwestern University, Chicago
RecruitingHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Aug 20, 2026 · NCT06511505

Role of Adiposomes in Endothelial Dysfunction

  • University of Illinois at Chicago, Chicago
Recruiting
Ages 18 to 50 · All sexes · Updated Aug 17, 2026 · NCT05199454

Study of the Progression of Chronic Cardiovascular Conditions

  • Prolaio, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07420907

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Advocate Health System, Downers Grove
  • Heart Care Centers of Illinois (HCCI), Palos Park
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Aspirin and Preeclampsia

  • University of Chicago Hospital, Chicago
RecruitingPhase 4
Ages 18 to 45 · Women · Updated May 4, 2026 · NCT04479072

Pivotal Study for the Cardiac Performance System (CPS)

  • Endeavor Health, Evanston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Advocate Good Samaritan, Downers Grove
  • Midwest Cardiovascular Institute (MCI), Naperville
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

  • Northwestern University Feinberg School of Medicine, Chicago
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

Biobank Cardiac Surgery

  • The University of Chicago, Hyde Park
RecruitingObservational study
All ages · All sexes · Updated Dec 19, 2025 · NCT06747806

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

  • Endotronix, Naperville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT06783335

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

  • Loyola University Medical Center, Maywood
Recruiting
Ages 18 to 80 · All sexes · Updated Sep 11, 2025 · NCT06271590

PARTNER 3 Trial - Aortic Valve-in-Valve

  • Northwestern University Hospital, Chicago
  • Rush University Medical Center, Chicago
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.