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Study of the Progression of Chronic Cardiovascular Conditions

RecruitingObservational study

A Non-interventional Observational Study of the Sustained Use of Prolaio Digital Health Devices to Monitor the Natural History of Chronic Cardiovascular Conditions in Ambulatory Patients

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* 18 years of age and older
* Ability to understand study assessments and give informed consent to data collection
* Ability to comply with the study protocol
* Ability to understand and respond to instructions in English
* Has diagnosis of qualifying Cardiovascular Disease(s), including but not limited to: HF, AS, HCM, HTN, DCM, etc. Additional CVD may be included at discretion of the investigators.
* Resides in the United States

Exclusion Criteria:

* Allergy to adhesive used in biosensor patch
* Life-threatening disease process outside of area under study, such as actively treated cancer or being actively considered for organ pre-transplant (such as hepatic failure; end-stage renal disease).
* Severe CVD defined by hospital admission for cardiac diagnosis within 30 days of enrollment or documentation of NYHA functional class IV
* \-- For participants who do not qualify due to this exclusion, and have not been hospitalized within 30 days of enrollment, they may reapply to enroll in the study
* Self-reported weight of 400 pounds or greater

About the study

This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.

Sponsor: Prolaio · Participants: 5,000 · Started: Oct 30, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07420907

Locations in the U.S.

IllinoisProlaio, Chicago

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.