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Cardiovascular Disease clinical trials in Indiana

19 studies for Cardiovascular Disease are looking for participants at sites in Indiana.

Cities in Indiana

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

  • Clinical Trial Site, Avon
  • Clinical Trial Site, Carmel
  • Clinical Trial Site, Evansville
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07181109

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  • American Health Network - Avon, Avon
  • Midwest Cardiovascular Research and Education Foundation, Elkhart
  • American Health Network - Greenfield, Greenfield
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473

INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

  • Ascension St. Vincent, Indianapolis
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504

Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)

  • Innovative Hematology, Indianapolis
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07601425

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • St. Vincent Hospital, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Franciscan Physician Network - Indiana Heart Physicians, Indianapolis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07783802

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

  • Midwest Cardiovascular Research and Education Foundation, Elkhart
  • Heart Center of Lake County, Merrillville
  • Reid Physician Associates, Richmond
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06909565

Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)

  • Ascension Saint Vincent Hospital - Indianapolis, Indianapolis
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 26, 2026 · NCT07585968

TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)

  • Ascension St. Vincent's Hospital, Carmel
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07684313

Product Surveillance Registry

  • Evansville
  • Indianapolis
RecruitingObservational study
All ages · All sexes · Updated Oct 20, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

  • Methodist Hospital of Indiana, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT04875429

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Indianapolis VA Medical Center, Indianapolis
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

  • Research Site, Evansville
  • Research Site, Evansville
  • Research Site, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

  • MediSphere Medical Research Center LLC, Evansville
  • Parkview Research Center, Fort Wayne
  • Franciscan Health Indianapolis, Indianapolis
  • and 3 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Ketone Ester And Salt (KEAS) in Older Adults

  • School of Public Health, Bloomington
RecruitingHealthy volunteers welcome
Ages 50 to 85 · All sexes · Updated Aug 19, 2026 · NCT06868719

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Ascension St. Vincent's, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Pediatric Cardiomyopathy Mutation Analysis

  • IU School of Medicine, Indianapolis
RecruitingObservational study
All ages · All sexes · Updated Jun 22, 2026 · NCT02432092

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

  • Indiana University School of Medicine, Indianapolis
RecruitingObservational study
All ages · All sexes · Updated Jun 22, 2026 · NCT02432079

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Community Health Network, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.