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Cardiovascular Disease clinical trials in Indianapolis, IN

15 studies for Cardiovascular Disease are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Franciscan Physician Network - Indiana Heart Physicians, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07783802

Product Surveillance Registry

RecruitingObservational study
  • Indianapolis, Indianapolis
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

RecruitingPhase 3
  • Clinical Trial Site, Avon · 13 mi away
  • Clinical Trial Site, Whiteland · 16 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Methodist Hospital of Indiana, Indianapolis
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • American Health Network - Avon, Avon · 13 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07064473

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Ascension St. Vincent Hospital - Indianapolis, Indianapolis
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Krannert Institute of Cardiology, Indianapolis
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Indianapolis VA Medical Center, Indianapolis
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Indianapolis
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Franciscan Health Indianapolis, Indianapolis
  • Ascension Saint Vincent Heart Center, Indianapolis
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Ascension St. Vincent's, Indianapolis
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

RecruitingObservational study
  • Indiana University School of Medicine, Indianapolis
All ages · All sexes · Updated Jun 22, 2026 · NCT02432079

Pediatric Cardiomyopathy Mutation Analysis

RecruitingObservational study
  • IU School of Medicine, Indianapolis
All ages · All sexes · Updated Jun 22, 2026 · NCT02432092

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • St. Vincent Hospital, Indianapolis
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Cardiovascular Disease trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.