Home › Cardiovascular Disease › Massachusetts
Cardiovascular Disease clinical trials in Massachusetts
39 studies for Cardiovascular Disease are looking for participants at sites in Massachusetts.
Cities in Massachusetts
ELEVATE-HFpEF Clinical Study
- Tufts Medical Center, Boston
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Boston Medical Center, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 1, 2026 · NCT07214376A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
- K2 Medical Research - Foxborough, Foxborough
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
- ActivMed Practices & Research, Methuen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06244199A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
- Bringham and Women's Hospital, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 28, 2026 · NCT07286578A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
- Massachusetts General Hospital, Boston
RecruitingPhase 3
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294CV CARE: CardioVascular Care in PC Patients
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT06202820Product Surveillance Registry
- Boston
- Holyoke
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276Zenith® Fenestrated+ Clinical Study
- Beth Israel Deaconess Medical Center, Boston
- University of Massachusetts, Worcester
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
- Massachusetts General Hospital, Boston
- Brigham and Women's Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Tufts Medical Center, Boston
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
- MGH, Boston
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
- Clinical Research Site, Boston
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
- Massachusetts General Hospital, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07601425Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- VA Boston Healthcare System, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Boston
- Research Site, Boston
- Research Site, Brookline
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- Brigham and Womens Hospital, Boston
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012Groceries for Residents of Southeastern USA to Stop Hypertension
- Beth Israel Deaconess Medical Center, Boston
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06891911Global Paradise System US Post Approval Study
- Massachusetts General Hospital, Boston
- The Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291The Oxford Risk Factors And Non-Invasive Imaging Study
- Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Jul 31, 2026 · NCT05169333PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Tufts Medical Center, Boston
- Boston Medical Center Corporation, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487SPYRAL GEMINI Pilot Study
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147EVOC - EVs in Obesity and Cardiometabolic Disease
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06408961Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation
- Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07174622WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
- Mass General Brigham Hospital, Boston
Recruiting
Ages 21 to 85 · All sexes · Updated Apr 13, 2026 · NCT07523269The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- St Elizabeth's Medical Center, Boston
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
- Joslin Diabetes Center, Boston
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302PKP2-ACM Natural History Study
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT05931276Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
- New Balance Foundation Obesity Prevention Center, Boston
RecruitingHealthy volunteers welcome
Ages 9 to 12 · All sexes · Updated Jan 8, 2026 · NCT05464186Determining the Benefits of Exercise on Cardiovascular Risk in PTSD
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 65 · All sexes · Updated Dec 2, 2025 · NCT07260032Impact of Cognitive Behavioral Therapy on PTSD-CVD Link
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 65 · All sexes · Updated Sep 25, 2025 · NCT06429293Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV
- Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Sep 22, 2025 · NCT06001814MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331Treatment of Brain AVMs (TOBAS) Study
- Boston Medical Center, Boston
Recruiting
Ages 5 and older · All sexes · Updated Aug 15, 2024 · NCT02098252PARTNER 3 Trial - Aortic Valve-in-Valve
- Brigham and Women's Hospital, Boston
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.