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Chronic Pain clinical trials in California

25 studies for Chronic Pain are looking for participants at sites in California.

Cities in California

Multisite Advancement of Research on Chronic Posttraumatic Headache

  • VA Greater Los Angeles Healthcare System, Los Angeles
  • VA Palo Alto Health Care System, Palo Alto
Recruiting
Ages 18 to 70 · All sexes · Updated Sep 22, 2026 · NCT05620719

Opioid and Pain Treatment in Indigenous Communities (OPTIC) Trial

  • Clinic Site A (blinded pending tribal approval), Arcata
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06565416

Patient Retrospective Outcomes (PRO)

  • MarinHealth Spine Institute, Larkspur
  • Loma Linda University Medical Center, Loma Linda
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT01550575

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

  • Desert Oasis Healthcare Medical Group, Palm Springs
  • Artemis Institute for Clinical Research, Riverside
  • Artemis Institute for Clinical Research, San Diego
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07641517

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

  • Desert Oasis Healthcare Medical Group, Palm Springs
  • Artemis Institute for Clinical Research, Riverside
  • Artemis Institute for Clinical Research, San Diego
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07641504

Post Market Evaluation of Real World Outcomes and Durability to Support Implantable Inceptiv™ Spinal Cord Stimulation Therapy

  • Relieve Pain Center, San Diego
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07507422

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
Recruiting
Ages 60 to 95 · All sexes · Updated Aug 28, 2026 · NCT06004804

RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain

  • VA San Diego Healthcare System, San Diego, CA, San Diego
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT05963607

A Pragmatic Trial of EAET for Veterans With Chronic Pain

  • University of California, Los Angeles, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07218757

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

  • VA Greater Los Angeles Healthcare System, Westwood campus, Los Angeles
  • West Los Angeles Veteran Affairs, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05790239

Pain and Major Depressive Disorder

  • UCLA Semel Institute, Los Angeles
RecruitingMentions payment for participants
Ages 18 to 75 · All sexes · Updated Aug 11, 2026 · NCT04556890

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

  • University of California, San Francisco, San Francisco
Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT04144972

Integrating Nonpharmacologic Strategies for Pain With Inclusion, Respect, and Equity

  • San Francisco General Hospital, San Francisco
  • UCSF Adult Primary Care Mt. Zion Clinic, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06183281

Group-based Integrative Pain Management in Primary Care Safety Net Clinics

  • Tom Waddell Urban Health Clinic, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06327542

Stanford Pragmatic Effectiveness Comparison

  • Stanford Pain Management Center, Redwood City
RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT04441034

NT-II™ Collagen for Joint Discomfort and Function

  • Alethios Inc., San Francisco
Recruiting
Ages 20 to 65 · All sexes · Updated May 14, 2026 · NCT07119645

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

  • SCAN Health Plan, Long Beach
Recruiting
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT05612750

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

  • Stanford University Medical Center, Stanford
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated May 6, 2026 · NCT06027099

Studying Melatonin and Recovery in Teens

  • Lucile Packard Children's Hospital, Palo Alto
Recruiting
Ages 12 to 18 · All sexes · Updated Mar 18, 2026 · NCT06093477

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

  • UCSD Health, La Jolla
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Feb 3, 2026 · NCT06387290

Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain

  • Palo Alto VA Medical Center, Palo Alto
Recruiting
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT06704061

Virtual 1-Session Spanish "Empowered Relief" Group Intervention for Chronic Pain

  • 1070 Arastradero Rd, Palo Alto
Recruiting
Ages 18 and older · All sexes · Updated Dec 22, 2025 · NCT04546685

A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

  • University of California, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Up to age 16 · All sexes · Updated Oct 23, 2025 · NCT06354699

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

  • VA Palo Alto Healthcare System, Palo Alto
RecruitingObservational study
Ages 25 to 80 · All sexes · Updated Aug 7, 2025 · NCT05700682

Assessment of Methadone Dose Taken

  • Synergy, Lemon Grove
RecruitingObservational study
Ages 18 to 70 · All sexes · Updated Feb 13, 2025 · NCT05981573

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.