A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

RecruitingObservational studyHealthy volunteers welcome

POPSICLE (Postoperative Pain Study in Children - a Longitudinal Evaluation)

Who can join

Up to age 16 · All sexes · Healthy volunteers welcome

Full eligibility criteria

Inclusion Criteria:

The patient is undergoing a surgical procedure in either group elective (circumcision, hypospadias, orchidopexy, laparoscopic appendicectomy) or group emergency (laparoscopic appendicectomy, scrotal exploration)

Exclusion Criteria:

The parent and child have inadequate English language skills to understand the questionnaires

Children with significant/severe developmental or cognitive delay based on a formal diagnosis.

Families that are unable to complete the long-term follow up surveys.

About the study

The purpose of this study is to investigate the prevalence, risk factors and consequences of chronic post-surgical pain in children aged 0-16 years through a number of questionnaires completed at various timepoints, from before surgery up to 1 year post surgery.

Sponsor: Telethon Kids Institute · Participants: 5,000 · Started: Jun 26, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06354699

Locations in the U.S.

California	University of California, San Francisco (Not yet recruiting)
Colorado	Children's Hospital Colorado, Aurora (Not yet recruiting)
Illinois	Lurie Children's Hospital of Chicago, Chicago (Not yet recruiting)
Michigan	Children's Hospital of Michigan, Detroit (Not yet recruiting)
North Carolina	Atrium Health-Wake Forest Baptist, Winston-Salem (Not yet recruiting)
Texas	Children's Medical Center (Dallas), Dallas (Not yet recruiting) Texas childrens hospital, Houston (Not yet recruiting)

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.