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Colon Cancer clinical trials in Pennsylvania
18 studies for Colon Cancer are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
- Philadelphia9 studies
- Pittsburgh9 studies
- Allentown5 studies
- Hazleton4 studies
- Harrisburg3 studies
- Scranton3 studies
- York3 studies
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
- St. Luke's University Health Network ( Site 2014), Easton
- UPMC Hillman Cancer Center ( Site 2024), Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06997497A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
- Sidney Kimmel Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07458347Shield Post-Approval Study Protocol
- US Digestive Health at Blair, Altoona
- University of Pennsylvania, Philadelphia
- Health Living at Pottstown Medical Specialists, Inc, Pottstown
RecruitingObservational studyHealthy volunteers welcome
Ages 45 to 81 · All sexes · Updated Nov 12, 2026 · NCT06880055Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
- Lehigh Valley Hospital-Cedar Crest, Allentown
- UPMC Altoona, Altoona
- UPMC-Heritage Valley Health System Beaver, Beaver
- and 59 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05174169Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Christiana Care Health System-Concord Health Center, Chadds Ford
- and 8 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07283939Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
- Saint Luke's Cancer Center - Allentown, Allentown
- Saint Luke's University Hospital-Bethlehem Campus, Bethlehem
- Geisinger Medical Center, Danville
- and 10 more
Recruiting
Ages 45 to 70 · All sexes · Updated Nov 4, 2026 · NCT05080673Distance-Based Exercise to Preserve Function and Prevent Disability
- UPMC Hillman Cancer Center at Butler Health System, Butler
- UPMC Hillman Cancer Center - Passavant - Cranberry, Cranberry Township
- IRMC Cancer Center, Indiana
- and 6 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884Family Communications After Genetic Testing
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Pocono Medical Center, East Stroudsburg
- and 2 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07143487A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
- Alliance Cancer Specialists, Doylestown
- Penn State Milton S. Hershey Medical Center, Hershey
- University of Pennsylvania, Philadelphia
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07284849Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- Allegheny Health Network, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Prehabilitation in High-risk Oncologic Surgery
- Fox Chase Cancer Center - Philadelphia, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07638410ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- University of Pennsylvania, Philadelphia
- WellSpan Medical Oncology & Hematology at York Cancer Center, York
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)
- Allegheny General Hospital, Pittsburgh
- Magee-Womens Hospital of UPMC, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07058012A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
- Alliance Cancer Specialists, Wynnewood
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
- University of Pittsburg Medical Center (UPCM), Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07223424SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
- Penn State Milton S. Hershey Medical Center, Hershey
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.