Home › Colon Cancer
Colon Cancer clinical trials recruiting in the U.S.
101 studies for Colon Cancer are recruiting participants at sites across the United States.
Cities with the most studies
- Boston, MA22 studies
- New York City, NY22 studies
- Houston, TX20 studies
- Los Angeles, CA16 studies
- Nashville, TN16 studies
- Arlington, VA15 studies
- St. Louis, MO15 studies
- San Antonio, TX14 studies
- Chicago, IL13 studies
- Tampa, FL13 studies
- Baldwin Park, CA13 studies
- Baltimore, MD13 studies
- Seattle, WA12 studies
- Durham, NC12 studies
- Washington, DC12 studies
- Grand Rapids, MI11 studies
- Cincinnati, OH11 studies
- Columbus, OH10 studies
- Sacramento, CA10 studies
- Rochester, MN9 studies
- Phoenix, AZ9 studies
- Salt Lake City, UT9 studies
- Philadelphia, PA9 studies
- Portland, OR9 studies
- Jacksonville, FL9 studies
- San Diego, CA9 studies
- Omaha, NE9 studies
- Atlanta, GA9 studies
- Denver, CO9 studies
- Aurora, CO9 studies
- Pittsburgh, PA9 studies
- Kansas City, MO8 studies
- Lexington, KY8 studies
- Edison, NJ8 studies
- Dallas, TX8 studies
- Cedar Rapids, IA8 studies
- Cleveland, OH8 studies
- Minneapolis, MN7 studies
- Green Bay, WI7 studies
- New Haven, CT7 studies
By state
- Alabama6 studies
- Arizona18 studies
- Arkansas6 studies
- California40 studies
- Colorado19 studies
- Connecticut10 studies
- Delaware3 studies
- District of Columbia5 studies
- Florida29 studies
- Georgia14 studies
- Hawaii4 studies
- Idaho8 studies
- Illinois18 studies
- Indiana7 studies
- Iowa9 studies
- Kansas7 studies
- Kentucky9 studies
- Louisiana8 studies
- Maine5 studies
- Maryland22 studies
- Massachusetts24 studies
- Michigan18 studies
- Minnesota18 studies
- Mississippi5 studies
- Missouri18 studies
- Montana7 studies
- Nebraska10 studies
- Nevada5 studies
- New Jersey14 studies
- New Mexico7 studies
- New York27 studies
- North Carolina20 studies
- North Dakota6 studies
- Ohio22 studies
- Oklahoma7 studies
- Oregon10 studies
- Pennsylvania18 studies
- Rhode Island3 studies
- South Carolina5 studies
- South Dakota8 studies
- Tennessee21 studies
- Texas29 studies
- Utah13 studies
- Virginia23 studies
- Washington14 studies
- West Virginia5 studies
- Wisconsin11 studies
- Wyoming3 studies
Recently updated studies
Genomic Services Research Program
RecruitingObservational study
1 Month – 105 Years · All sexes · Updated Sep 28, 2026 · NCT02595957Collection of Blood From Patients With Cancer
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT00034216A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Prehabilitation in High-risk Oncologic Surgery
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07638410A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444Evaluating Novel Therapies in ctDNA Positive GI Cancers
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05482516Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial
Recruiting
Ages 18 to 50 · All sexes · Updated Sep 11, 2026 · NCT06202183Resilience and Equity in Aging, Cancer, and Health (REACH)
Recruiting
Ages 65 and older · All sexes · Updated Sep 10, 2026 · NCT04674267A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07058012PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05868226Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939Family Communications After Genetic Testing
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
RecruitingObservational study
Ages 18 to 50 · Women · Updated Sep 2, 2026 · NCT06904365A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07321106Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
RecruitingPhase 1
Ages 18 to 120 · All sexes · Updated Aug 26, 2026 · NCT06885697BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07594626From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.