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Colon Cancer clinical trials in Tennessee

22 studies for Colon Cancer are looking for participants at sites in Tennessee.

Cities in Tennessee

Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer

  • Investigator Site, Nashville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07808151

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

  • Baptist Memorial Hospital and Cancer Center-Collierville, Collierville
  • The West Clinic - Wolf River, Germantown
  • Covenant Health Cancer Centers, Knoxville
  • and 5 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05174169

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Baptist Memorial Hospital and Cancer Center-Collierville, Collierville
  • Baptist Memorial Hospital and Cancer Center-Memphis, Memphis
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07283939

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Baptist Memorial Hospital and Cancer Center-Memphis, Memphis
Recruiting
Ages 45 to 70 · All sexes · Updated Nov 4, 2026 · NCT05080673

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

  • Provision Center For Biomedical Research, Knoxville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07284849

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Henry-Joyce Cancer Clinic, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07222800

A Study of PHN-012 in Patients With Advanced Solid Tumors

  • PHN-012-001 Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Sarah Cannon Research Institue, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • Tennessee Oncology, PLLC, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

  • GSK Investigational Site, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

  • Xencor Investigative Site, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

  • Sarah Cannon, SCRI Oncology Partners, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT04678648

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

  • SCRI Oncology Partners, Nashville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • Baptist Memorial Hospital Baptist Cancer Center, Memphis
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • Tennessee Oncology, Chattanooga
  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

  • Veterans Affairs Medical Center - Nashville, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT00899626

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Memphis
  • Massive Bio SYNERGY-AI site, Nashville
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.