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Dementia clinical trials in Massachusetts
17 studies for Dementia are looking for participants at sites in Massachusetts.
Cities in Massachusetts
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Local Institution - 0080, Watertown
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type
- Vitalix, Worcester
RecruitingPhase 2
All ages · All sexes · Updated Sep 16, 2026 · NCT06052254Making Connections Thru Music
- Hopeful Aging, Winchester
- The Hearthstone Institute, LLC, Winchester
RecruitingHealthy volunteers welcome
Ages 18 to 103 · All sexes · Updated Sep 15, 2026 · NCT06079216The BRAIN App (Phase 2 SBIR)
- Hopeful Aging, Winchester
Recruiting
Ages 65 and older · All sexes · Updated Sep 15, 2026 · NCT06298474Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 70 and older · All sexes · Updated Sep 14, 2026 · NCT06052397Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- VA Boston Healthcare System, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
- Massachusetts General Hospital (MGH), Charlestown
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Boston Center for Memory, Newton
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
- Hebrew Rehabilitation Center, Roslindale
Recruiting
Ages 65 to 90 · All sexes · Updated Jul 16, 2026 · NCT06821568A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
- Boston Center for Memory, Newton
- MedVadis Research Corporation, Waltham
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
- ActivMed Practices and Research, Methuen
RecruitingPhase 2
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516Trial-Ready Cohort-Down Syndrome (TRC-DS)
- Massachusetts General Hospital, Co-Enrolling through ABC-DS Only, Boston
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
- Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 60 to 85 · All sexes · Updated Feb 12, 2026 · NCT06489548Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
- Hinda and Arthur Marcus Institute for Aging Research, Boston
Recruiting
Ages 55 and older · All sexes · Updated Jan 12, 2026 · NCT05661084Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
- Hebrew SeniorLife, Boston
Recruiting
Ages 60 to 106 · All sexes · Updated Jan 6, 2026 · NCT05950607Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
- McLean Hospital, Belmont
RecruitingObservational study
Ages 18 to 89 · All sexes · Updated Nov 6, 2025 · NCT05245903Assess Fibrin in Brains With AD/ADRD
- Massachusetts General Hospital, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 55 to 90 · All sexes · Updated Oct 30, 2025 · NCT05336695From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.