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Dementia clinical trials in Boston, MA

8 studies for Dementia are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium

RecruitingObservational study
  • Massachusetts General Hospital, Boston
Ages 70 and older · All sexes · Updated Sep 14, 2026 · NCT06052397

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • VA Boston Healthcare System, Boston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
  • Massachusetts General Hospital (MGH), Charlestown · 1 mi away
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Massachusetts General Hospital, Co-Enrolling through ABC-DS Only, Boston
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

RecruitingPhase 2
  • Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston
Ages 60 to 85 · All sexes · Updated Feb 12, 2026 · NCT06489548

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Recruiting
  • Hinda and Arthur Marcus Institute for Aging Research, Boston
Ages 55 and older · All sexes · Updated Jan 12, 2026 · NCT05661084

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Recruiting
  • Hebrew SeniorLife, Boston
Ages 60 to 106 · All sexes · Updated Jan 6, 2026 · NCT05950607

Assess Fibrin in Brains With AD/ADRD

RecruitingPhase 1/2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 55 to 90 · All sexes · Updated Oct 30, 2025 · NCT05336695

About Dementia

People with dementia have serious problems with two or more brain functions, such as memory and language. Affects the ability to do normal activities.

More about Dementia on MedlinePlus

Dementia trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.