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Depression clinical trials in Maryland
29 studies for Depression are looking for participants at sites in Maryland.
Cities in Maryland
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Oct 1, 2026 · NCT05703685Natural History of Depression, Bipolar Disorder and Suicide Risk
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 1, 2026 · NCT06462196Long-term Observation of Participants With Mood Disorders
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Oct 1, 2026 · NCT04877977A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
- Pharmasite Research, Inc., Baltimore
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07775300Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 99 · All sexes · Updated Sep 28, 2026 · NCT00024635Characterization and Treatment of Adolescent Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 11 to 25 · All sexes · Updated Sep 28, 2026 · NCT03388606A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
- Delricht Research - Rockville, Rockville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
- Sunstone Medical, PC, Rockville
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT03065335RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Sunstone Therapies, PC, Rockville
- Sheppard Pratt, Towson
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 14, 2026 · NCT06511908Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT03973268Neurobiology of Suicide
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT02543983A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
- Pharmasite Research Inc., Baltimore
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407Psilocybin in Chronic Low Back Pain and Depression
- Johns Hopkins University School of Medicine, Baltimore
RecruitingPhase 1
Ages 21 to 80 · All sexes · Updated Sep 4, 2026 · NCT06355414Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
- Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore
RecruitingEarly phase 1
Ages 18 to 85 · All sexes · Updated Sep 4, 2026 · NCT04123314A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
- Draig Clinical Site, Gaithersburg
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07300969PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 18, 2026 · NCT04582916A Study of Brenipatide in Adult Participants With Major Depressive Disorder
- Pharmasite Research, Inc., Baltimore
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756E-Mindfulness Approaches for Living After Breast Cancer
- Maryland Proton Treatment Center, Baltimore
- University of Maryland/Greenebaum Cancer Center, Baltimore
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
- and 14 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Gaithersburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401Strength and Pain-Coping Through Resilience and Knowledge
- Johns Hopkins School of Nursing, Baltimore
Recruiting
Ages 50 and older · All sexes · Updated Jul 22, 2026 · NCT07228520CAPABLE Transplant
- Johns Hopkins School of Nursing, Baltimore
Recruiting
Ages 18 to 99 · All sexes · Updated Jul 20, 2026 · NCT06326905CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
- Walter Reed National Medical Military Center, Bethesda
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05663034A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Sheppard Pratt Health System, Inc., Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Sheppard Pratt, Baltimore
- Sunstone Medical, PC, Rockville
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study
- Johns Hopkins University, Baltimore
Recruiting
Ages 18 and older · Women · Updated May 6, 2026 · NCT07227337VR-PMR for Post-Burn Symptoms
- Johns Hopkins Bayview Medical Center, Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07317271Glucose Variability and Cognition in Prediabetes
- Baltimore VA Geriatric Research Education and Clinical Center (GRECC), Baltimore
RecruitingObservational studyHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Mar 30, 2025 · NCT04201600From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.