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Depression clinical trials in Baltimore, MD

14 studies for Depression are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Sheppard Pratt, Towson · 8 mi away
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

RecruitingPhase 3
  • Pharmasite Research Inc., Baltimore
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407

Psilocybin in Chronic Low Back Pain and Depression

RecruitingPhase 1
  • Johns Hopkins University School of Medicine, Baltimore
Ages 21 to 80 · All sexes · Updated Sep 4, 2026 · NCT06355414

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

RecruitingEarly phase 1
  • Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore
Ages 18 to 85 · All sexes · Updated Sep 4, 2026 · NCT04123314

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

RecruitingPhase 3
  • Pharmasite Research, Inc., Baltimore
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Maryland Proton Treatment Center, Baltimore
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
  • and 7 more
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Strength and Pain-Coping Through Resilience and Knowledge

Recruiting
  • Johns Hopkins School of Nursing, Baltimore
Ages 50 and older · All sexes · Updated Jul 22, 2026 · NCT07228520

CAPABLE Transplant

Recruiting
  • Johns Hopkins School of Nursing, Baltimore
Ages 18 to 99 · All sexes · Updated Jul 20, 2026 · NCT06326905

Clinical Trial on Agitation in Alzheimer's Dementia

RecruitingPhase 2
  • MedStar Franklin Square Medical Center Neurology, Baltimore
Ages 60 and older · All sexes · Updated May 20, 2026 · NCT05543681

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Sheppard Pratt, Baltimore
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

Recruiting
  • Johns Hopkins University, Baltimore
Ages 18 and older · Women · Updated May 6, 2026 · NCT07227337

VR-PMR for Post-Burn Symptoms

Recruiting
  • Johns Hopkins Bayview Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07317271

Glucose Variability and Cognition in Prediabetes

RecruitingObservational studyHealthy volunteers welcome
  • Baltimore VA Geriatric Research Education and Clinical Center (GRECC), Baltimore
Ages 50 and older · All sexes · Updated Mar 30, 2025 · NCT04201600

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.