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Down Syndrome clinical trials in California
10 studies for Down Syndrome are looking for participants at sites in California.
Cities in California
Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
- Cedars-Sinai Medical Center, Los Angeles
- Sharp-Rees Stealy Medical Group, San Diego
- UCSD, San Diego
- and 2 more
RecruitingObservational study
Ages 18 and older · Women · Updated Sep 9, 2026 · NCT01429389Endotype DIrected Treatment for OSA in Down Syndrome
- University of California San Diego, San Diego
RecruitingPhase 4
Ages 6 and older · All sexes · Updated Sep 3, 2026 · NCT07280468A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
- Kaiser Permanente-Anaheim, Anaheim
- Kaiser Permanente Downey Medical Center, Downey
- Kaiser Permanente-Fontana, Fontana
- and 14 more
RecruitingPhase 2
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
- Valley Children's Hospital, Madera
- UCSF Benioff Children's Hospital Oakland, Oakland
- Kaiser Permanente-Oakland, Oakland
- and 3 more
RecruitingObservational study
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Lucile Packard Children's Hospital, Palo Alto
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment
- San Gabriel Valley Perinatal Medical Group, West Covina
RecruitingObservational study
All ages · Women · Updated Jun 12, 2026 · NCT07643896Collaboration for Down Syndrome Progress (CDP)
- University of California Irvine, Orange
RecruitingObservational study
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579Trial-Ready Cohort-Down Syndrome (TRC-DS)
- University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only, Orange
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109Down Syndrome Obstructive Sleep Apnea
- Children's Hospital of Los Angeles, Los Angeles
RecruitingPhase 2
Ages 5 to 18 · All sexes · Updated Apr 20, 2025 · NCT06043440Pediatric Down Syndrome Post-Approval Study
- Children's Hospital Orange County, Orange
Recruiting
Ages 13 to 18 · All sexes · Updated Feb 28, 2025 · NCT06851338From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.