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Emphysema clinical trials recruiting in the U.S.
19 studies for Emphysema are recruiting participants at sites across the United States.
Emphysema is a type of COPD. COPD makes it hard to breathe. The most common cause of Emphysema is smoking. Learn about symptoms and treatment.
Cities with the most studies
- Boston, MA8 studies
- Chicago, IL7 studies
- Pittsburgh, PA4 studies
- Houston, TX4 studies
- Philadelphia, PA4 studies
- Orlando, FL4 studies
- Birmingham, AL4 studies
- Milwaukee, WI3 studies
- Cleveland, OH3 studies
- Dallas, TX3 studies
- Phoenix, AZ3 studies
- New York City, NY3 studies
By state
- Alabama4 studies
- Arizona4 studies
- California8 studies
- Colorado3 studies
- Florida6 studies
- Illinois8 studies
- Massachusetts9 studies
- Michigan3 studies
- New York4 studies
- Ohio3 studies
- Pennsylvania7 studies
- South Carolina3 studies
- Texas6 studies
- Wisconsin3 studies
Recently updated studies
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
RecruitingPhase 2
Ages 40 to 75 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07759245Gene Therapy for Alpha 1- Antitrypsin Deficiency
RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06996756An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Recruiting
Ages 40 to 80 ยท All sexes ยท Updated Sep 17, 2026 ยท NCT06035120Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
Recruiting
Ages 40 to 75 ยท All sexes ยท Updated Aug 28, 2026 ยท NCT05257681A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
RecruitingPhase 3
Ages 18 to 80 ยท All sexes ยท Updated Aug 11, 2026 ยท NCT07555483STRIVE Post-Market Registry Study
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Aug 3, 2026 ยท NCT04302272A Multi Center Study Testing a New Implant for Adults With Severe Emphysema
Recruiting
Ages 22 and older ยท All sexes ยท Updated Jun 3, 2026 ยท NCT07119229Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Recruiting
Ages 40 to 84 ยท All sexes ยท Updated Apr 24, 2026 ยท NCT06891755Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema
Recruiting
Ages 40 to 75 ยท All sexes ยท Updated Apr 13, 2026 ยท NCT04801108PiMZ Longitudinal Cohort (PiMZ Logic)
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Jan 16, 2026 ยท NCT06505603Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure
RecruitingPhase 1/2
Ages 18 to 60 ยท All sexes ยท Updated Jan 13, 2026 ยท NCT03500731Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 14, 2025 ยท NCT01776398Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
Recruiting
Ages 40 and older ยท All sexes ยท Updated Oct 30, 2025 ยท NCT07059637Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study
RecruitingObservational study
All ages ยท All sexes ยท Updated Oct 24, 2025 ยท NCT01177618Emphysema Research Registry and Biosample Repository
RecruitingObservational studyHealthy volunteers welcome
Ages 21 and older ยท All sexes ยท Updated Sep 25, 2025 ยท NCT00307281COPD Resources, Education, and Activity Designed for You Study
Recruiting
Ages 40 and older ยท All sexes ยท Updated Sep 22, 2025 ยท NCT07125053Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
RecruitingObservational study
Ages 50 and older ยท All sexes ยท Updated Aug 5, 2025 ยท NCT06122077Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older ยท All sexes ยท Updated Oct 27, 2023 ยท NCT03263130COPD Patient-Powered Research Network
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Mar 10, 2022 ยท NCT02803242From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.