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Endometrial Cancer clinical trials in Sioux Falls, SD

11 studies for Endometrial Cancer are looking for participants at sites in and around Sioux Falls (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Sanford Cancer Center Oncology Clinic, Sioux Falls
  • Sanford USD Medical Center - Sioux Falls, Sioux Falls
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Avera Medical Group, Sioux Falls
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

RecruitingPhase 3
  • Sanford Cancer Center, Sioux Falls
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT06340568

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

RecruitingPhase 2
  • Sanford Health, Sioux Falls
Ages 18 and older · Women · Updated Aug 21, 2026 · NCT05548296

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

RecruitingPhase 3
  • Research Site, Sioux Falls
  • Research Site, Sioux Falls
Ages 18 and older · Women · Updated Jul 29, 2026 · NCT07044336

Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer

RecruitingPhase 3
  • Avera Medical Group Gynecologic Oncology Sioux Falls, Sioux Falls
  • Texas Oncology, P.A. - Tyler, Sioux Falls
Ages 18 and older · Women · Updated Jul 28, 2026 · NCT07022483

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Avera Cancer Institute, Sioux Falls
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Avera Cancer Sequencing and Analytics Protocol (ASAP)

RecruitingObservational study
  • Avera Cancer Institute, Sioux Falls
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT05142033

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

RecruitingPhase 2
  • Avera Cancer Institute, Sioux Falls
Ages 18 and older · Women · Updated Dec 24, 2025 · NCT06463028

A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

RecruitingPhase 2
  • Avera Medical Group Oncology, Sioux Falls
Ages 18 to 70 · Women · Updated Oct 30, 2025 · NCT06481592

Endometrial Cancer trials in other cities

Other studies in Sioux Falls

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.