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Heart Failure clinical trials in Sioux Falls, SD

7 studies for Heart Failure are looking for participants at sites in and around Sioux Falls (within about 30 miles). Open a study to see who can join and how to contact the study team.

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

Recruiting
  • North Central Heart, Sioux Falls
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07232030

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • Avera Heart Hospital of South Dakota, Sioux Falls
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738

NORM-HF Pivotal Study

Recruiting
  • North Central Heart - Avera Hospital, Sioux Falls
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07574593

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • North Central Heart, Sioux Falls
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Sanford, Sioux Falls
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • North Central Heart-Avera, Sioux Falls
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

RecruitingObservational study
  • Sanford Health, Sioux Falls
Ages 18 to 100 · All sexes · Updated May 22, 2024 · NCT06425848

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Sioux Falls

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.