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Epilepsy clinical trials in Massachusetts
23 studies for Epilepsy are looking for participants at sites in Massachusetts.
Cities in Massachusetts
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
- Brigham and Women's Hospital, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06388707Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110454Diagnosing Epilepsy To EffeCT Change
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110337AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
- Massachusetts General Hospital, Boston
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT06063850Subcortical Arousal in Perceptual Awareness
- Massachusetts General Hospital, Boston
Recruiting
Ages 13 and older · All sexes · Updated Aug 10, 2026 · NCT06934356A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
- Brigham and Women's Hospital, Chestnut Hill
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Aug 10, 2026 · NCT05667142Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies
- Boston Children's Hospital, Boston
RecruitingPhase 1
0 Days – 9 Months · All sexes · Updated Jul 6, 2026 · NCT06700811Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
- Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Jun 9, 2026 · NCT05135091Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application
- University of Massachusetts Chan Medical School, Worcester
Recruiting
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT06425029Computational Neuroscience of Language Processing in the Human Brain
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated May 7, 2026 · NCT05222594PET/MRI/EEG Imaging Study in Epilepsy
- Athinoula A. Martinos Center, Charlestown
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06974305Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT04419272A Multicenter Pediatric Deep Brain Stimulation Registry
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 0 to 18 · All sexes · Updated Mar 18, 2026 · NCT06585618A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 0 to 18 · All sexes · Updated Mar 18, 2026 · NCT06585605Infrared Photobiomodulation in Humans With Epilepsy
- BIDMC, Boston
Recruiting
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT07145489Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
- Boston Children's Hospital, Boston
RecruitingPhase 2
1 Day – 6 Months · All sexes · Updated Jan 22, 2026 · NCT05104983Genetics of Epilepsy and Related Disorders
- Boston Children's Hospital, Boston
RecruitingObservational study
All ages · All sexes · Updated Jan 9, 2026 · NCT01858285Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 6 and older · All sexes · Updated Dec 17, 2025 · NCT05944692Ear-Seizure Detection (EarSD) Study
- Ummmc-Memorial Campus, Worcester
- Ummmc-University Campus, Worcester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 28, 2025 · NCT06598189Registry and Natural History of Epilepsy-Dyskinesia Syndromes
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 0 to 30 · All sexes · Updated Aug 17, 2025 · NCT06967727Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking
- Empatica, Boston
Recruiting
Ages 6 and older · All sexes · Updated Sep 19, 2024 · NCT06275685Epilepsy Learning Healthcare System (ELHS)
- Partners - Massachusetts General Hospital Epilepsy Service (MGH)/ Partners - Brigham and Women's (BWH), Boston
- Brigham & Women's Hospital, Boston
RecruitingObservational study
All ages · All sexes · Updated Aug 30, 2024 · NCT06265103Human Epilepsy Genetics--Neuronal Migration Disorders Study
- Boston Children's Hospital, Walsh Laboratory, Boston
RecruitingObservational study
All ages · All sexes · Updated Sep 21, 2023 · NCT00041600From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.