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Head and Neck Cancer clinical trials in Pennsylvania
20 studies for Head and Neck Cancer are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
DESTINY-PANTUMOUR04
- Research Site, Philadelphia
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000A Pilot Study of Ultra-High Dose Rate (ConformalFLASH®), for Reirradiation of Carcinoma of the Head and Neck
- The University of Pennsylvania, Department of Radiation Oncology, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07644585A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
- UPMC, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07020117The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Abramson Cancer Center of the University of Pennsylvania, Philadelphia
- University of Pittsburgh Medical Center, Pittsburgh
- WellSpan York Cancer Center, York
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
- University of Pennsylvania, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06125743Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
- Pennsylvania State University, Hershey
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05442957Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients
- UMPC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT07631650Distance-Based Exercise to Preserve Function and Prevent Disability
- UPMC Hillman Cancer Center at Butler Health System, Butler
- IRMC Cancer Center, Indiana
- UPMC Hillman Cancer Center - New Castle, New Castle
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07059884Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT05388773FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
- Site #0103, Pittsburgh
- Site #0123, Pittsburgh
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT06788990Lead-212 PSV359 Therapy for Patients With Solid Tumors
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations
- Fox Chase Cancer Center, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT06030011Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema
- University of Pennsylvania Abramson Cancer Center, Philadelphia
Recruiting
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06837480A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
- GSK Investigational Site, Philadelphia
- GSK Investigational Site, Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT07501650The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
- Allegheny Health Network, Pittsburgh
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Cancer Care Associates of York (site 206), York
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System
- University of Pittsburgh Medical Center, Pittsburgh
RecruitingObservational study
All ages · All sexes · Updated Aug 15, 2025 · NCT05406167Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.