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Heart Failure clinical trials in Indiana

29 studies for Heart Failure are looking for participants at sites in Indiana.

Cities in Indiana

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

  • Research Site, Elkhart
  • Research Site, Evansville
  • Research Site, Muncie
  • and 1 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 2, 2026 · NCT06307652

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

  • Midwest Cardiovascular Research and Education Foundation, Elkhart
  • St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis
  • Cardiovascular Research of Northwest Indiana, LLC, Munster
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06935370

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

  • Midwest Cardiovascular Research and Education Foundation, Elkhart
  • St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis
  • Indiana Medical Research Institute, Merrillville
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06424288

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

  • Research Site, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

  • Cardiovascular Research of Northwest Indiana, LLC., Munster
  • Deaconess Heart Group, Newburgh
  • Reid Physician Associates, Richmond
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Midwest Cardiovascular Research And Education Foundation, Elkhart
  • Ascension Medical Group, Indianapolis
  • Cardiovascular Research of Northwest Indiana LLC, Munster
  • and 1 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

  • Research Site, Indianapolis
  • Research Site, Munster
  • Research Site, Richmond
  • and 1 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

  • CON-10064, Merrillville, IN, Merrillville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

  • Indianapolis, IN Investigative Site 10074, Indianapolis
  • Indianapolis, IN Investigative Site 10008, Indianapolis
  • Merrillville, IN Investigative Site 10064, Merrillville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Ascension St. Vincent Hospital - Indianapolis, Indianapolis
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

  • Community Heart and Vascular Hospital, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738

A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)

  • Local Institution - 166, Indianapolis
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

  • Evansville
  • Indianapolis
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

  • Indiana. University, Indianapolis
  • Franciscan Physician Network-Indiana Heart Physicians, Indianapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

  • Tenax Investigational Site, Indianapolis
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Asha Clinical Rsch-Munster, LLC, Hammond
  • Indiana University Health Methodist Hospital, Indianapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Alleviant ALLAY-HF Study

  • Indiana University, Indianapolis
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

Assessment of CCM in HF With Higher Ejection Fraction

  • Ascension Medical Group St. Vincent, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

  • Riley Hospital For Children - Cardiology, Indianapolis
RecruitingPhase 3
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • Ascension St. Vincent's, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Pediatric Cardiomyopathy Mutation Analysis

  • IU School of Medicine, Indianapolis
RecruitingObservational study
All ages · All sexes · Updated Jun 22, 2026 · NCT02432092

Palliative Care for People With HF

  • IUHealth, Indianapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT07356843

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • St. Vincent Hospital, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

  • NexGen Research, Fort Wayne
  • Reid Physician Associates, Richmond
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated May 27, 2026 · NCT06991257

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Community Health Network, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Left vs Left Randomized Clinical Trial

  • Trustees of Indiana University, Indianapolis
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

  • Indiana University, Bloomington
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated May 22, 2024 · NCT06425848

From ClinicalTrials.gov, data retrieved Oct 3, 2026. Each study sets its own eligibility; the study team decides who can join.