Home › Heart Failure › Kentucky
Heart Failure clinical trials in Kentucky
21 studies for Heart Failure are looking for participants at sites in Kentucky.
Cities in Kentucky
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Owensboro
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Norton Heart Specialists, Louisville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- The Research Group of Lexington LLC, Lexington
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Lexington
- Research Site, Louisville
- Research Site, Owensboro
- and 1 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Cynthiana, KY Investigative Site 10124, Cynthiana
- Lexington, KY Investigative Site 10080, Lexington
- Lexington, KY Investigative Site 10118, Lexington
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- CON-10080, Lexington, KY, Lexington
- Lexington, KY Investigative Site CON-10118, Lexington
- CON-10086, Louisville, Kentucky, Louisville
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- University of Kentucky, Lexington
- University of Louisville, Louisville
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Baptist Hospital East Louisville, Louisville
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 160, Cynthiana
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Edgewood
- Louisville
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- The Research Group of Lexington LLC, Lexington
- UofL Health Care Outpatient, Louisville
- Research Integrity Global, LLC, Owensboro
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- St. Elizabeth Healthcare, Edgewood
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303Assessment of CCM in HF With Higher Ejection Fraction
- Baptist Health Lexington, Lexington
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- UofL Health Care Outpatient, Louisville
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Aug 5, 2026 · NCT06979362ELEVATE-HFpEF Clinical Study
- Norton Healthcare, Louisville
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Cynthiana, KY Investigative Site FIN-10124, Cynthiana
- FIN-10080, Lexington, KY, Lexington
- Lexington, KY Investigative Site FIN-10118, Lexington
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- University of Kentucky, Lexington
- Norton Hospital, Louisville
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies
- Jia-Rong Wu, Lexington
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT05548413Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients
- University of Kentucky, Lexington
Recruiting
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT05537467Left vs Left Randomized Clinical Trial
- Baptist Health Louisville, Louisville
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
- St. Elizabeth Healthcare, Edgewood
RecruitingObservational study
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.