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Heart Failure clinical trials in Lexington, KY

11 studies for Heart Failure are looking for participants at sites in and around Lexington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • The Research Group of Lexington LLC, Lexington
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Lexington
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

RecruitingPhase 3
  • CON-10080, Lexington, KY, Lexington
  • Lexington, KY Investigative Site CON-10118, Lexington
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Lexington, KY Investigative Site 10080, Lexington
  • Lexington, KY Investigative Site 10118, Lexington
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • University of Kentucky, Lexington
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • The Research Group of Lexington LLC, Lexington
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • Baptist Health Lexington, Lexington
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

RecruitingPhase 3
  • FIN-10080, Lexington, KY, Lexington
  • Lexington, KY Investigative Site FIN-10118, Lexington
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of Kentucky, Lexington
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies

RecruitingHealthy volunteers welcome
  • Jia-Rong Wu, Lexington
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT05548413

Effect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients

Recruiting
  • University of Kentucky, Lexington
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT05537467

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Lexington

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.