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Heart Failure clinical trials in Massachusetts
47 studies for Heart Failure are looking for participants at sites in Massachusetts.
Cities in Massachusetts
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- Boston Children's Hospital ( Site 0035), Boston
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Nov 13, 2026 · NCT05714085Left vs Left Randomized Clinical Trial
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05650658A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Boston Medical Center, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376PrEcision Pacing in HFpEF: the PEP-HFpEF Trial
- Tufts Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07864558Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- Tufts Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07232030Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Boston
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Tufts Medical Center, Boston
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Southcoast Physicians Group, Fall River
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738ELEVATE-HFpEF Clinical Study
- Tufts Medical Center, Boston
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- Boston Children's Hospital - Main Campus - Cardiology, Boston
RecruitingPhase 3
Up to age 18 · All sexes · Updated Oct 27, 2026 · NCT07192952Voice-based Outcome Identification and Clinical Evaluation in Heart Failure
- Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 22 and older · All sexes · Updated Oct 27, 2026 · NCT07870395CCM OPEN HF Registry
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07112924Cardiogenic Shock Working Group Registry
- Tufts Medical Center, Boston
- Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT04682483Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
- Tufts Medical Center, Boston
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Oct 26, 2026 · NCT06253104Assessment of CCM in HF With Higher Ejection Fraction
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Boston
- Research Site, Roslindale
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060NORM-HF Pivotal Study
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07574593A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- Boston Children's Hospital - Main Campus - Cardiology, Boston
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Oct 15, 2026 · NCT07188805Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Boston
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652Alleviant ALLAY-HFrEF Study
- Tufts Medical Center, Boston
- Brigham and Women's Hospital, Boston
- Boston Medical Center, Boston
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
- Mass General Brigham, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
- Mass General Brigham, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Boston
- Research Site, Boston
- Research Site, New Bedford
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Boston, MA Investigative Stie 10087, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
- Massachusetts General Hospital, Boston
Recruiting
Ages 65 and older · All sexes · Updated Sep 1, 2026 · NCT05577819Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT03480633Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)
- Mass General Brigham, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Aug 31, 2026 · NCT07337577AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Harvard (Massachusetts General Hospital), Boston
- Harvard Medical School - Brigham and Women's Hospital (BWH), Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705Alleviant ALLAY-HF Study
- Brigham and Women's Hospital, Boston
- Boston Medical Center, Boston
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Tufts Medical Center, Boston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751Care Transitions App for Patients With Multiple Chronic Conditions
- Brigham and Women's Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Jul 9, 2026 · NCT06051058The STOP-MED CTRCD Trial
- Brigham and Women's Hospital, Boston
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06183437PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Tufts Medical Center, Boston
- Boston Medical Center Corporation, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Promoting Well-being and Health in Heart Failure
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT04829617The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- St Elizabeth's Medical Center, Boston
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess, Boston
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
- Joslin Diabetes Center, Boston
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302Home Hospital for Suddenly Ill Adults
- Brigham and Women's Hospital, Boston
- Brigham and Women's Faulkner Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT03524222From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.