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Heart Failure clinical trials in South Carolina
30 studies for Heart Failure are looking for participants at sites in South Carolina.
Cities in South Carolina
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Spartanburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Medical University of South Carolina - Gazes Research Institute, Charleston
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Bon Secours Medical Group Greenville Specialty Care, LLC, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Alleviant ALLAY-HFrEF Study
- Roper St. Francis Healthcare, Charleston
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Columbia
- Research Site, Fort Mill
- Research Site, Mt. Pleasant
- and 2 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Charleston
- Research Site, Charleston
- Research Site, Lancaster
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Charleston, SC Investigative Site 10056, Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- MUSC, Charleston
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 10, 2026 · NCT07098858Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 142, Charleston
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- AnMed Health, Anderson
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Columbia
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Charleston
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Prisma Health - Upstate, Greenville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Med. Uni. of SC Ashley River T, Charleston
- Piedmont Research Partners, LLC, Fort Mill
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Medical University of South Carolina, Charleston
- Prisma Health - Midlands, Colombia
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751Assessment of CCM in HF With Higher Ejection Fraction
- Prisma Health Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709ELEVATE-HFpEF Clinical Study
- Medical University of South Carolina (MUSC), Charleston
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Orangeburg, SC Investigative Site FIN-10433, Orangeburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- Medical University of South Carolina, Charleston
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Jun 30, 2026 · NCT07137338A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- MUSC Shawn Jenkins Children's Hospital - Cardiology, North Charleston
RecruitingPhase 3
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Medical University of South Carolina (MUSC), Charleston
- PRISMA Health- Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- MUSC Shawn Jenkins Children's Hospital - Cardiology, North Charleston
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Jun 15, 2026 · NCT07188805Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Medical University of South Carolina, Charleston
- Prisma Health Midlands, Columbia
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Precision Rehabilitation for Veterans With (HFpEF)
- Columbia VA Health Care System, Columbia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 25, 2026 · NCT07493915Left vs Left Randomized Clinical Trial
- Medical University of South Carolina (MUSC), Charleston
- Prisma Health-Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
- Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 14 to 65 · All sexes · Updated Nov 1, 2024 · NCT06311708HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
- Prisma Health, Columbia
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated May 22, 2024 · NCT06425848From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.