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Heart Failure clinical trials in South Carolina
29 studies for Heart Failure are looking for participants at sites in South Carolina.
Cities in South Carolina
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Bon Secours Medical Group Greenville Specialty Care, LLC, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06424288Left vs Left Randomized Clinical Trial
- Medical University of South Carolina (MUSC), Charleston
- Prisma Health-Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05650658Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Medical University of South Carolina, Charleston
- Prisma Health Midlands, Columbia
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Columbia
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Medical University of South Carolina - Gazes Research Institute, Charleston
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574ELEVATE-HFpEF Clinical Study
- Medical University of South Carolina (MUSC), Charleston
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- MUSC Shawn Jenkins Children's Hospital - Cardiology, North Charleston
RecruitingPhase 3
Up to age 18 · All sexes · Updated Oct 27, 2026 · NCT07192952Assessment of CCM in HF With Higher Ejection Fraction
- Prisma Health Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Columbia
- Research Site, Fort Mill
- Research Site, Goose Creek
- and 3 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- MUSC, Charleston
RecruitingObservational study
Ages 22 and older · All sexes · Updated Oct 16, 2026 · NCT07098858NORM-HF Pivotal Study
- Prisma Health - Midlands, Columbia
- Prisma Health - Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07574593A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- MUSC Shawn Jenkins Children's Hospital - Cardiology, North Charleston
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Oct 15, 2026 · NCT07188805A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 17, Charleston
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Oct 13, 2026 · NCT07795814Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Charleston
- Research Site, Charleston
- Research Site, Lancaster
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652Alleviant ALLAY-HFrEF Study
- Roper St. Francis Healthcare, Charleston
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- Medical University of South Carolina, Charleston
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Spartanburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
- Medical University of South Carolina, Charleston
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Charleston, SC Investigative Site 10056, Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- AnMed Health, Anderson
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Prisma Health - Upstate, Greenville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Med. Uni. of SC Ashley River T, Charleston
- Piedmont Research Partners, LLC, Fort Mill
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Medical University of South Carolina, Charleston
- Prisma Health - Midlands, Colombia
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Orangeburg, SC Investigative Site FIN-10433, Orangeburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Medical University of South Carolina (MUSC), Charleston
- PRISMA Health- Upstate, Greenville
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Precision Rehabilitation for Veterans With (HFpEF)
- Columbia VA Health Care System, Columbia
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 25, 2026 · NCT07493915Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
- Medical University of South Carolina, Charleston
RecruitingObservational study
Ages 14 to 65 · All sexes · Updated Nov 1, 2024 · NCT06311708HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
- Prisma Health, Columbia
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated May 22, 2024 · NCT06425848From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.