HIV clinical trials in California
33 studies for HIV are looking for participants at sites in California.
Cities in California
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
- GSK Investigational Site, Bakersfield
- GSK Investigational Site, Los Angeles
- GSK Investigational Site, Los Angeles
- and 2 more
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 28, 2026 · NCT07650916El Camino HIV Prevention and Care Study
- Oasis Legal Services, Berkeley
Recruiting
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07834853A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
- Ruane Clinical Research Group, Inc. ( Site 1513), Los Angeles
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07266831Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
- Bridge HIV CRS, San Francisco
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
- Pacific Oaks Medical Group, Beverly Hills
- Ruane Clinical Research Group Inc., Los Angeles
- Family Health Centers of San Diego, San Diego
- and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07473778Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
- 5048, University of Southern California Clinical Research Site, Los Angeles
- 5112, David Geffen School of Medicine at UCLA Clinical Research Site, Los Angeles
RecruitingPhase 1/2
48 Hours · All sexes · Updated Sep 9, 2026 · NCT02140255SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era
- San Francisco General Hospital, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT00187512Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
- UC San Diego Moores Cancer Center, La Jolla
Recruiting
Ages 45 to 80 · All sexes · Updated Aug 19, 2026 · NCT04949464Positive Peers Intervention Clinical Trial
- Northeast Valley Health Corporation, Van Nuys
Recruiting
Ages 13 to 34 · All sexes · Updated Aug 18, 2026 · NCT06388109Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy
- Optimus Medical Group, San Francisco
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07682961A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV
- UC San Diego Altman Clinical and Translational Research Institute, La Jolla
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07143968A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
- GSK Investigational Site, Bakersfield
- GSK Investigational Site, Palm Springs
- GSK Investigational Site, West Hollywood
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07202546Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
- City of Hope Comprehensive Cancer Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05077527Sexual Health Advocacy for Guys - a Text Messaging-based HIV Prevention Program for Guys Who Are Into Guys
- Center for Innovative Public Health Research, San Clemente
- Center for Innovative Public Health Research, San Clemente
RecruitingHealthy volunteers welcome
Ages 13 to 22 · Men · Updated Jul 9, 2026 · NCT06230367Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care
- University of California, San Diego, San Diego
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT05241990Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
- University of California, Davis, Sacramento
- University of California, San Diego, San Diego
- University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06263426Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
- UC San Diego Moores Cancer Center, La Jolla
- University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05663502Menopausal HT for Women Living With HIV (HoT)
- University of California, Los Angeles CARE Center CRS (601), Los Angeles
- UCSD Antiviral Research Center CRS (701), San Diego
- 801 University of California, San Francisco HIV/AIDS CRS, San Francisco
- and 1 more
RecruitingPhase 4
Ages 40 to 60 · Women · Updated May 22, 2026 · NCT06856174Cefixime Clinical Trial
- University of Southern California, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 4, 2026 · NCT04958122Women Focused Encounters for Resilience Independence Strength and Eudaimonia
- UC San Diego AntiViral Research Center (AVRC), San Diego
RecruitingHealthy volunteers welcome
Ages 18 and older · Women · Updated May 1, 2026 · NCT06216600CAR-T Cells for HIV Infection
- University of California, Davis, Sacramento
- Zuckerberg San Francisco General, San Francisco
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Apr 9, 2026 · NCT04648046Teamwork Makes the Dream Work
- Loma Linda University Medical Center, Loma Linda
Recruiting
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT05866523An Integrated Intervention Using a Pill Ingestible Sensor System
- Lundquist, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06480578SCOPE Analytic Treatment Interruption Protocol
- University of California San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT04359186Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
- UCLA Center for Clinical AIDS Research and Education (CARE), Los Angeles
- San Francisco General Hospital, San Francisco
RecruitingPhase 2
Ages 40 and older · All sexes · Updated Dec 17, 2025 · NCT05488431Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement
- The Regents of the Univ. of Calif., U.C. San Diego, La Jolla
Recruiting
Ages 18 and older · Women · Updated Oct 20, 2025 · NCT05509959Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically
- University of California, Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 3, 2025 · NCT06370780Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
- Bridge HIV, San Francisco Department of Public Health, San Francisco
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 25, 2025 · NCT06796686Feasibility of HPV Testing With Mail-delivered Sample Collection Kits
- University of California, San Francisco, San Francisco
RecruitingObservational study
Ages 35 and older · All sexes · Updated Aug 1, 2025 · NCT07087145Text Education About Cardiovascular Health and HIV (TEACH-HIV)
- Zuckerberg San Francisco General Hospital, San Francisco
- University of California San Francisco, San Francisco
Recruiting
Ages 40 and older · All sexes · Updated Jun 8, 2025 · NCT05642858Imaging Immune Activation in HIV by PET-MR
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 24, 2024 · NCT03684655Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics
- GSK Investigational Site, Long Beach
RecruitingPhase 1/2
Ages 6 to 12 · All sexes · Updated Sep 19, 2024 · NCT05674656Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
- San Francisco AIDS Foundation, San Francisco
RecruitingHealthy volunteers welcome
Ages 15 and older · All sexes · Updated Sep 28, 2022 · NCT04855773From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.