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Leiomyosarcoma clinical trials in Houston, TX

7 studies for Leiomyosarcoma are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

RecruitingPhase 1/2
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498648

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

RecruitingPhase 3
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04031677

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT05711615

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
  • NEXT Houston, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06975293

A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07633756

Metastatic Leiomyosarcoma Biomarker Protocol

RecruitingObservational study
  • MD Anderson, Houston
All ages · All sexes · Updated Jun 24, 2026 · NCT05653388

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06789172

Leiomyosarcoma trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.