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Liver Cancer clinical trials in California

24 studies for Liver Cancer are looking for participants at sites in California.

Cities in California

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT04907643

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

  • Providence St. Jude, Fullerton
  • Cedars-Sinai Medical Center, Los Angeles
  • Mission Hospital, Mission Viejo
  • and 3 more
RecruitingObservational study
Ages 22 and older · All sexes · Updated Nov 6, 2026 · NCT06486454

CREO - Microwave Ablation Feasibility Study

  • Cedars Sinai, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07817147

Distance-Based Exercise to Preserve Function and Prevent Disability

  • Kaiser Permanente Dublin, Dublin
  • Kaiser Permanente-Fremont, Fremont
  • Kaiser Permanente Fresno Orchard Plaza, Fresno
  • and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

  • Clinical Trial Site, La Jolla
  • Clinical Trial Site, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06600321

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

  • Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07223307

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

  • Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • UCI Health - Irvine Infusion Pharmacy ACC, Irvine
  • UCI Health - Irvine, Irvine
  • and 8 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07227012

National Liver Cancer Screening Trial

  • University of Southern California, Los Angeles
  • Stanford University, Redwood City
  • Kaiser Permanente, Roseville
  • and 1 more
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

DESTINY-PANTUMOUR04

  • Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

  • City of Hope National Medical Center /ID# 270526, Duarte
  • City of Hope - Orange County Lennar Foundation Cancer Center /ID# 276120, Irvine
  • USC Norris Comprehensive Cancer Center /ID# 271573, Los Angeles
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06858813

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

  • City of Hope, Duarte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04864054

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • USC/Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

  • Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06580002

Multi-analyte Blood Test Clinical Trial

  • Gastroenterology and Liver Institute, Escondido
  • Providence Facey Medical Foundation, Mission Hills
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT05199259

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

  • City of Hope Medical Center, Duarte
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06342414

A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

  • USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07337525

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

  • Children's Hospital Los Angeles, Los Angeles
  • Children's Hospital Orange County, Orange
  • UCSF Benioff Children's Hospitals, San Francisco
RecruitingPhase 1/2
Ages 1 to 21 · All sexes · Updated Jul 6, 2026 · NCT04634357

Project for Multi-Omics-Based Early Detection of Hepatocellular Carcinoma (PROMETHEA Study)

  • City of Hope Medical Center, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07265271

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

  • VA Long Beach Healthcare System, Long Beach, CA, Long Beach
  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
  • VA Northern California Health Care System, Mather, CA, Sacramento
  • and 2 more
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

  • Start Lacn, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07517198

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

  • Chao Family Comprehensive Cancer Center, University of California Irvine, Orange
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07447050

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

  • University of California San Francisco, San Francisco
RecruitingPhase 2
Ages 0 to 30 · All sexes · Updated Feb 24, 2026 · NCT04134559

Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology

  • VA Palo Alto Healthcare System, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 26, 2025 · NCT07303725

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Duarte
  • Massive Bio SYNERGY-AI site, Irvine
  • Massive Bio SYNERGY-AI site, La Jolla
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.