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Liver Cancer clinical trials recruiting in the U.S.
65 studies for Liver Cancer are recruiting participants at sites across the United States.
The most common form of liver cancer in adults is hepatocellular carcinoma. Learn about diagnosis, treatment and taking part in research studies.
Cities with the most studies
- Houston, TX13 studies
- Los Angeles, CA11 studies
- Dallas, TX10 studies
- Cleveland, OH10 studies
- Boston, MA9 studies
- Chicago, IL8 studies
- Philadelphia, PA7 studies
- Durham, NC7 studies
- St. Louis, MO7 studies
- Washington, DC6 studies
- San Francisco, CA6 studies
- New York City, NY6 studies
- Orange, CA6 studies
- Pittsburgh, PA6 studies
- Baldwin Park, CA5 studies
- Seattle, WA5 studies
- Nashville, TN5 studies
- Ann Arbor, MI4 studies
- Richmond, VA4 studies
- San Diego, CA4 studies
- Mountain View, CA4 studies
- Aurora, CO4 studies
- Baltimore, MD4 studies
- Rochester, MN4 studies
- Columbus, OH3 studies
- New Rochelle, NY3 studies
- The Bronx, NY3 studies
- Santa Monica, CA3 studies
- Birmingham, AL3 studies
- Atlanta, GA3 studies
- Miami, FL3 studies
- Portland, OR3 studies
- Omaha, NE3 studies
- Irvine, CA3 studies
- Highlands Ranch, CO3 studies
- Winston-Salem, NC3 studies
- Kansas City, MO3 studies
- Tampa, FL3 studies
- San Antonio, TX3 studies
By state
- Alabama4 studies
- Arizona5 studies
- Arkansas3 studies
- California24 studies
- Colorado7 studies
- Connecticut3 studies
- Florida10 studies
- Georgia4 studies
- Illinois11 studies
- Kansas3 studies
- Maryland9 studies
- Massachusetts11 studies
- Michigan5 studies
- Minnesota8 studies
- Missouri10 studies
- Nebraska3 studies
- New York10 studies
- North Carolina11 studies
- Ohio14 studies
- Oklahoma3 studies
- Oregon3 studies
- Pennsylvania14 studies
- Tennessee6 studies
- Texas23 studies
- Utah3 studies
- Virginia8 studies
- Washington5 studies
- Wisconsin5 studies
Recently updated studies
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Recruiting
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT04907643Collection of Blood From Patients With Cancer
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT00034216Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT00451022Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
RecruitingObservational study
Ages 22 and older · All sexes · Updated Nov 6, 2026 · NCT06486454CREO - Microwave Ablation Feasibility Study
Recruiting
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07817147Distance-Based Exercise to Preserve Function and Prevent Disability
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Oct 30, 2026 · NCT07430202Cancer Experience Registry (CER) for Cancer Patients and Caregivers
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT02333604A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT06600321REGULUS: MRI-guided Adaptive SABR for Liver Cancers
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07223307Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients
Recruiting
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT04933435GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies
RecruitingPhase 1
Ages 18 to 120 · All sexes · Updated Oct 16, 2026 · NCT05003895Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT03551951Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 8, 2026 · NCT07227012National Liver Cancer Screening Trial
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234DESTINY-PANTUMOUR04
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Protoacoustic Imaging For 3D Mapping
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07832617A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06858813A Study Evaluating a New Radiation Treatment Workflow (NGDS)
Recruiting
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT07824583EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088Defining the Ablative Dose for Y-90 TARE
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07586046GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04864054A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Aug 24, 2026 · NCT05517811From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.