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Lung Cancer clinical trials in Denver, CO

16 studies for Lung Cancer are looking for participants at sites in and around Denver (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
  • National Jewish Health-Main Campus, Denver
  • Rocky Mountain Cancer Centers - Swedish, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT04267848

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
  • Rocky Mountain Cancer Centers - Swedish, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT04181060

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06498635

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

RecruitingPhase 1
  • Presbyterian/St Lukes Medical Center, Denver
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Rocky Mountain Cancer Center, Denver
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Denver
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Kaiser Permanente-Franklin, Denver
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Porter, Denver
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • Sarah Cannon Research Institute - Denver DDU, Denver
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • UCHealth - Cherry Creek, Denver
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

RecruitingPhase 1
  • Sarah Cannon, SCRI Oncology Partners - Health One, Denver
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT04678648

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

RecruitingPhase 1/2
  • Sarah Cannon Research Institute Denver, Denver
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06922591

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) at HealthONE, Denver
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Denver
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Denver

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.