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Non-Small Cell Lung Cancer clinical trials in Denver, CO

27 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Denver (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
  • National Jewish Health-Main Campus, Denver
  • Rocky Mountain Cancer Centers - Swedish, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Rocky Mountain Cancer Center, Denver
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Kaiser Permanente-Franklin, Denver
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Rocky Mountain Cancer Centers,LLP, Denver
  • Rocky Mountain Cancer Centers LLP, Denver
  • Rocky Mountain Cancer Centers LLP, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

RecruitingPhase 1/2
  • Rocky Mountain Cancer Centers,LLP, Denver
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07227298

Pan-tumor MRD Study

RecruitingObservational study
  • The Melanoma and Skin Cancer Institute, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • SCRI at HCA HealthONE, Denver
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Denver
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Local Institution - 007-872-E, Denver
  • Local Institution - 007-872-I, Denver
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HCA HealthONE Presbyterian St. Luke's, Denver
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06914128

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute Denver, Denver
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

SMP-3124LP in Adults With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06526819

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institue At Healthone, Denver
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06179160

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Denver
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) at HealthONE, Denver
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente-Franklin, Denver
  • Colorado Blood Cancer Institute, Denver
  • Rocky Mountain Cancer Centers-Midtown, Denver
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

RecruitingPhase 1
  • Dren Investigational Site, Denver
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT06999187

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Denver
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

RecruitingPhase 1/2
  • HealthONE Clinic Services Oncology - Hematology, LLC d/b/a Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

Non-Small Cell Lung Cancer trials in other cities

Other studies in Denver

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.