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Melanoma clinical trials in Denver, CO

19 studies for Melanoma are looking for participants at sites in and around Denver (within about 30 miles). Open a study to see who can join and how to contact the study team.

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

RecruitingPhase 1
  • Presbyterian/St Lukes Medical Center, Denver
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • The Melanoma And Skin Cancer Institute, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Pan-tumor MRD Study

RecruitingObservational study
  • The Melanoma and Skin Cancer Institute, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Denver
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT06398418

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • The Women's Imaging Center, Denver
  • Colorado Blood Cancer Institute, Denver
  • Presbyterian - Saint Lukes Medical Center - Health One, Denver
  • and 6 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2
  • Skin Cancer Institute, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Porter, Denver
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute Denver, Denver
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

RecruitingPhase 1/2
  • SCRI Oncology Partners- Denver, Denver
Ages 18 to 70 · All sexes · Updated Jun 15, 2026 · NCT06940739

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

RecruitingPhase 1/2
  • SCRI - Denver, Denver
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT03947385

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • The Melanoma and Skin Cancer Institute, Englewood · 6 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

RecruitingPhase 2/3
  • University of Colorado, Denver
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06624644

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at Health ONE, Denver
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06326411

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • The Melanoma & Skin Cancer Institute, Englewood · 6 mi away
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente-Franklin, Denver
  • Colorado Blood Cancer Institute, Denver
  • Rocky Mountain Cancer Centers-Midtown, Denver
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Denver
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

RecruitingPhase 1/2
  • HealthONE Clinic Services Oncology - Hematology, LLC d/b/a Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Nov 15, 2024 · NCT04787042

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Denver

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.