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Lung Cancer clinical trials in Connecticut

31 studies for Lung Cancer are looking for participants at sites in Connecticut.

Cities in Connecticut

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

  • Smilow Cancer Hospital - Yale New Haven Health, New Haven
  • Yale - New Haven Hospital - Yale Cancer Center, New Haven
  • Smilow Cancer Hospital Phase 1 Unit, New Haven
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

  • Hartford HealthCare - Avon, Avon
  • Hartford Hospital, Hartford
  • Hartford HealthCare - Manchester, Manchester
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06498635

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • Smilow Cancer Hospital-Derby Care Center, Derby
  • Smilow Cancer Hospital Care Center-Fairfield, Fairfield
  • Smilow Cancer Hospital Care Center at Greenwich, Greenwich
  • and 9 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04267848

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • Yale Cancer Center, New Haven
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

  • Smilow Cancer Hospital-Derby Care Center, Derby
  • Smilow Cancer Hospital Care Center-Fairfield, Fairfield
  • Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
  • and 14 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT04181060

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

  • Stamford Hospital/Bennett Cancer Center, Stamford
  • Veterans Affairs Connecticut Healthcare System-West Haven Campus, West Haven
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Sep 24, 2026 · NCT06096844

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

  • Research Site, New Haven
RecruitingPhase 2
Ages 18 to 95 · All sexes · Updated Sep 23, 2026 · NCT05061550

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

  • Yale University, New Haven
  • Yale-New Haven Hospital North Haven Medical Center, North Haven
  • Smilow Cancer Hospital Care Center-Trumbull, Trumbull
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

  • Yale Cancer Center, New Haven
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • Yale University School of Medicine - Yale Cancer Center, New Haven
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Yale Cancer Center, New Haven
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Yale University School of Medicine, New Haven
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, New Haven
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

  • Yale Cancer Center, New Haven
  • Norwalk Hospital, Norwalk
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Veterans Affairs Connecticut Healthcare System-West Haven Campus, West Haven
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

  • Yale University, Smillow Cancer Center, New Haven
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06881784

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

  • Xencor Investigative Site, New Haven
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

  • Yale University Cancer Center, New Haven
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

Integrated Cancer Repository for Cancer Research

  • Hartford HealthCare Cancer Institute at Manchester Medical Hospital, Manchester
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

  • Smilow Cancer Hospital-Derby Care Center, Derby
  • Smilow Cancer Hospital Care Center-Fairfield, Fairfield
  • Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
  • and 11 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • Smilow Cancer Hospital (Yale University), New Haven
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

  • Smilow Cancer Hospital-Derby Care Center, Derby
  • Smilow Cancer Hospital Care Center-Fairfield, Fairfield
  • Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
  • and 10 more
RecruitingPhase 2
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

  • Smilow Cancer Hospital-Derby Care Center, Derby
  • Smilow Cancer Hospital Care Center-Fairfield, Fairfield
  • Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
  • and 10 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

  • Yale New Haven Medical Center, New Haven
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06196008

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Hartford Hospital (site 210), Hartford
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Hartford
  • Massive Bio SYNERGY-AI site, Norwalk
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)

  • Yale School of Medicine, New Haven
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 12, 2025 · NCT06412172

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

  • Stamford Hospital, Stamford
RecruitingObservational study
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

  • Trinity Health Of New England, Hartford
  • The Stamford Health/The Stamford Hospital, Stamford
RecruitingObservational study
Ages 29 to 85 · All sexes · Updated Nov 13, 2024 · NCT06426628

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.