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Lung Cancer clinical trials in New York

92 studies for Lung Cancer are looking for participants at sites in New York.

Cities in New York

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

  • WMCHealth Advanced Physician Services, Hawthorne
  • Local Institution - 0128, Rochester
  • Ellis Hospital, Schenectady
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07063745

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-based Chemotherapy With or Without Amivantamab for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola
  • NYU Langone Health, New York
  • Weill Cornell Medical College, New York
  • and 1 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07100080

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

  • Hematology Oncology Associates of Rockland, Nyack
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06758401

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

  • Montefiore Medical Center-Einstein Campus, The Bronx
  • Montefiore Medical Center-Weiler Hospital, The Bronx
  • Montefiore Medical Center - Moses Campus, The Bronx
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06498635

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • Northwell Health Imbert Cancer Center, Bay Shore
  • Maimonides Medical Center, Brooklyn
  • Roswell Park Cancer Institute, Buffalo
  • and 18 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04267848

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

  • Glens Falls Hospital, Glens Falls
  • Upstate Cancer Center at Oswego, Oswego
  • University of Rochester, Rochester
  • and 7 more
RecruitingPhase 3
Ages 70 and older · All sexes · Updated Nov 12, 2026 · NCT06096844

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

  • Laura & Isaac Perlmutter Cancer Center at NYU Langone, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07020221

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

  • Cayuga Medical Center ( Site 0086), Ithaca
  • University Hospital at Stony Brook ( Site 0054), Stony Brook
  • White Plains Hospital ( Site 0091), White Plains
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06312137

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

  • GSK Investigational Site, East Syracuse
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07099898

Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer

  • Roswell Park Cancer Institute, Buffalo
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07718672

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

  • SUNY Upstate Medical University, Syracuse
  • Montefiore Einstein Cancer Center, The Bronx
  • Clinical Research Alliance, Westbury
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06793215

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Queens Hospital Center, Jamaica
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • Stony Brook University Medical Center, Stony Brook
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

  • Roswell Park Cancer Institute, Buffalo
  • Memorial Sloan Kettering Commack, Commack
  • The Cancer Institute at Saint Francis Hospital, East Hills
  • and 13 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT04181060

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • NYU Langone Health - Long Island, Mineola
  • New York University (NYU) Clinical Cancer Center, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06400472

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • Weill Cornell Medicine, Cornell University (site 126), New York
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT03556228

A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

  • Local Institution - 0142, Buffalo
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07492680

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Maimonides Cancer Center, Brooklyn
  • Northwell Health/ RJ Zuckerberg Cancer Center, Lake Success
  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island, Mineola
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06119581

Longitudinal Evaluation of Microbial and Host Signatures During Immunotherapy for Lung Cancer

  • NYU Langone Health, New York
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Nov 3, 2026 · NCT04063501

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

  • Memorial Sloan Kettering (Melanoma/NSCLC), New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06060613

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

  • Nuvance Health, Poughkeepsie
  • Suny-Stony Brook University Cancer Center, Stony Brook
  • White Plains Hospital, White Plains
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06712316

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

  • Northwell Health/R.J. Zuckerberg Cancer Center, Lake Success
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
  • Columbia University Medical Center, New York
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07185997

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT06287775

A Study of a Side Effects and Resource Navigation Program for People With Cancer

  • Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities), Commack
  • Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison
  • City College of New York (Data Collection AND Specimen Analysis), New York
  • and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07646847

New York Better Breathing Study

  • Roswell Park Cancer Institute, Buffalo
Recruiting
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06869447

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06835569

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • Roswell Park Cancer Institute IDS, Buffalo
  • Memorial Sloan Kettering Hospital, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06172478

Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer

  • Roswell Park Cancer Institute, Buffalo
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05292521

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT06922591

Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

  • NYU Langone Health, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT03290534

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT06810544

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • New York Cancer & Blood Specialists, New York
  • University of Rochester - Wilmot Cancer Institute, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 20, 2026 · NCT06582017

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

  • New York University Langone Health, New York
  • Columbia University Medical Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 19, 2026 · NCT06162221

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, New York
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Oct 16, 2026 · NCT07038343

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

  • Cornell University - NewYork-Presbyterian/Weill Cornell Medical Center, New York
  • White Plains Hospital, White Plains
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 14, 2026 · NCT06712355

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05786924

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

  • Start (Nyli), Lake Success
  • NYU Langone Hospital - Long Island Investigational Pharmacy, Mineola
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT06293898

A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

  • Memorial Sloan Kettering Cancer Center - Commack, Commack
  • Memorial Sloan Kettering Cancer Center - Westchester, East White Plains
  • Long Island Jewish Medical Center, Lake Success
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT07128199

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

  • MSK Commack, Commack
  • MSK Westchester, Harrison
  • Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy, Long Island City
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT07476287

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

  • Memorial Sloan Kettering Commack, Commack
  • Memorial Sloan Kettering Westchester, Harrison
  • Memorial Sloan Kettering Cancer Center, New York
  • and 2 more
RecruitingPhase 2
18 Minutes · All sexes · Updated Oct 9, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

  • The Cancer Institute at Saint Francis Hospital, East Hills
  • University of Rochester, Rochester
  • Stony Brook University Medical Center, Stony Brook
  • and 4 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 9, 2026 · NCT06616584

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.