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Lupus clinical trials in California

27 studies for Lupus are looking for participants at sites in California.

Cities in California

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

  • Research Site, Fontana
  • Research Site, La Jolla
  • Research Site, La Palma
  • and 3 more
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 25, 2026 · NCT07430306

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

  • David S Hallegua MD A Professional Corporation, Beverly Hills
  • Providence Medical Foundation, Fullerton
  • Southland Arthritis and Osteoporosis Medical Center Inc dba Southland Arthritis, Hemet
  • and 5 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07438496

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

  • University of California Davis Comprehensive Cancer Center, Sacramento
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

  • Research Site, Fullerton
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Sep 18, 2026 · NCT07201558

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

  • Wallace & Lee Center, Beverly Hills
  • Arthritis & Osteoporosis Medical Center, Inc - La Palma, La Palma
  • University of California San Diego, San Diego
  • and 3 more
RecruitingPhase 2
Ages 18 to 74 · All sexes · Updated Sep 17, 2026 · NCT07409181

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

  • Inland Rheumatology Clinical Trials, Inc., Upland
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT07355218

Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

  • University of California San Francisco - Zuckerberg San Francisco General, San Francisco
RecruitingPhase 1
Ages 18 to 60 · All sexes · Updated Sep 14, 2026 · NCT06975787

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

  • Wallace Rheumatic Studies Center, Beverly Hills
  • Kaiser Permanente Fontana, Fontana
  • Providence Medical Foundation, Fullerton
  • and 2 more
RecruitingPhase 2
Ages 12 to 70 · All sexes · Updated Sep 14, 2026 · NCT07570862

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

  • Dermatology Research Associates - 300204025, Los Angeles
  • Cohen Medical Centers, Thousand Oaks
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07332481

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

  • Loma Linda University Medical Center, Loma Linda
RecruitingPhase 1
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

  • Research Site, Los Angeles
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Sep 10, 2026 · NCT05835310

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

  • Research Site, San Francisco
  • Research Site, Stanford
RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

  • Sl0044 50737, Beverly Hills
  • Sl0044 50775, Beverly Hills
  • Sl0044 50257, La Jolla
  • and 6 more
RecruitingPhase 3
Ages 16 and older · All sexes · Updated Sep 4, 2026 · NCT06617325

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

  • Local Institution - 0054, La Jolla
  • Local Institution - 0001, La Palma
  • Local Institution - 0071, Los Angeles
  • and 1 more
RecruitingObservational study
Ages 16 and older · All sexes · Updated Sep 3, 2026 · NCT07175285

FT839 in Autoimmune Diseases

  • Providence Medical Foundation, Fullerton
RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Sep 2, 2026 · NCT07800871

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

  • UC San Diego Health, La Jolla
  • Stanford University Medical Center, Redwood City
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

  • University of California Irvine, Orange
  • UC Davis Health, Sacramento
RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

  • University of California, Los Angeles, Los Angeles
  • University of California: San Diego, San Diego
RecruitingPhase 3
Ages 55 and older · All sexes · Updated Aug 20, 2026 · NCT05799378

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

  • Ronald Reagan UCLA Medical Center, Los Angeles
RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Jul 30, 2026 · NCT05268289

Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA

  • Carewell Arthritis Center, Apple Valley
  • Attune Health Research Inc, Beverly Hills
  • Covina Arthritis Clinic, Covina
  • and 4 more
RecruitingPhase 1
Ages 18 to 75 · All sexes · Updated Jul 20, 2026 · NCT07237659

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

  • Providence Medical Center, Burbank
  • Advanced Medical Research, La Palma
RecruitingPhase 3
Ages 12 to 100 · All sexes · Updated Jul 8, 2026 · NCT06133972

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

  • US06-0, La Palma
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Jun 2, 2026 · NCT06625671

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

  • Wallace Rheumatic Center, Beverly Hills
  • Providence Medical Foundation, Fullerton
  • University of California Irvine, Irvine
  • and 2 more
RecruitingPhase 1
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

Lupus Landmark Study: A Prospective Registry and Biorepository

  • Wallace Rheumatic Studies Center, Beverly Hills
  • UCLA, Los Angeles
RecruitingObservational study
Ages 18 to 110 · All sexes · Updated Apr 15, 2026 · NCT05934149

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.